| Entry |
|
|---|
| Name |
Alfentanil (INN);
Rapifen (TN) |
|---|
| Formula |
C21H32N6O3
|
|---|
| Exact mass |
416.2536
|
|---|
| Mol weight |
416.5172
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00792): | D00835<US> |
|
|---|
| Efficacy |
Analgesic (narcotic), Opioid receptor agonist |
|---|
| Comment |
synthetic opioid
Phenylpiperidine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AH Opioid anesthetics
N01AH02 Alfentanil
D07122 Alfentanil (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02026 Opioid anesthetics
DG00792 Alfentanil
D07122 Alfentanil
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00792 Alfentanil
D07122 Alfentanil
Analgesic
DG01984 Opioid analgesics
DG00792 Alfentanil
D07122 Alfentanil
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D07122 Alfentanil (INN)
Narcotics and psychotropics in Japan [br08308.html]
Narcotics by Cabinet Order Article 1 (157 substances)
D07122
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02026 Opioid anesthetics
DG00792 Alfentanil
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00792 Alfentanil
Analgesic
DG01984 Opioid analgesics
DG00792 Alfentanil
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 30
1 C8x C 17.1500 -27.4400
2 C8x C 17.1500 -28.8400
3 C8x C 18.3400 -29.5400
4 C8x C 19.6000 -28.8400
5 C8y C 19.6000 -27.4400
6 C8x C 18.3400 -26.7400
7 N1c N 20.7900 -26.7400
8 C1z C 22.0500 -27.4400
9 C1x C 22.0500 -28.8400
10 C1x C 23.2400 -29.5400
11 N1y N 24.4300 -28.8400
12 C1x C 24.4300 -27.4400
13 C1x C 23.2400 -26.7400
14 C1b C 25.6900 -29.5400
15 C1b C 26.8800 -28.8400
16 N4y N 28.0700 -29.5400
17 N5x N 28.4200 -30.8700
18 N5x N 29.8200 -30.8700
19 N4y N 30.3100 -29.6100
20 C8y C 29.1900 -28.7700
21 C5a C 20.7900 -25.3400
22 O5a O 19.6000 -24.6400
23 C1b C 22.0500 -24.6400
24 C1a C 23.2400 -25.3400
25 C1b C 20.7900 -28.1400
26 O2a O 20.7900 -29.5400
27 C1a C 19.6000 -30.2400
28 O5x O 29.1900 -27.3700
29 C1b C 31.5000 -28.9100
30 C1a C 32.6900 -29.6100
BOND 32
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 8 13 1
15 11 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 2
20 18 19 1
21 19 20 1
22 16 20 1
23 7 21 1
24 21 22 2
25 21 23 1
26 23 24 1
27 8 25 1
28 25 26 1
29 26 27 1
30 20 28 2
31 29 30 1
32 29 19 1
|
|---|
