KEGG DRUG: Treosulfan

DRUG: Treosulfan

Entry

D07253                      Drug

Name

Treosulfan (USAN/INN);
Ovastat (TN)

Formula

C6H14O8S2

Exact mass

278.013

Mol weight

278.3006

Structure

Simcomp

Class

Antineoplastic
DG01677 Alkylating agent
DG01721 Methanesulfonate derivative

Remark

Same as:

C19557

ATC code:

L01AB02

Efficacy

Antineoplastic, Alkylating agent

Comment

Part of conditioning treatment prior to allogeneic hematopoietic stem cell transplantation (alloHSCT).

Target

DNA

Interaction

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01A ALKYLATING AGENTS
    L01AB Alkyl sulfonates
     L01AB02 Treosulfan
      D07253  Treosulfan (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
  DG01677  Alkylating agent
   DG01721  Methanesulfonate derivative
    D07253  Treosulfan
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
  D07253

Other DBs

CAS:

299-75-2

PubChem:

ChEBI:

LigandBox:

NIKKAJI:

KCF data

ATOM        16
            1   O2a O    29.8900  -18.0600
            2   C1b C    28.7000  -18.7600
            3   C1c C    27.5100  -18.0600
            4   C1c C    26.2500  -18.7600
            5   C1b C    25.0600  -18.0600
            6   O2a O    23.8700  -18.7600
            7   O1a O    27.5100  -16.6600
            8   O1a O    26.2500  -20.1600
            9   S4a S    22.6100  -18.0600
            10  C1a C    23.3100  -16.8000
            11  O3c O    21.4200  -17.3600
            12  O3c O    21.9100  -19.2500
            13  S4a S    31.1500  -18.7600
            14  C1a C    30.4500  -19.9500
            15  O3c O    31.8500  -17.5000
            16  O3c O    32.3400  -19.4600
BOND        15
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     3   7 1 #Up
            7     4   8 1 #Up
            8     6   9 1
            9     9  10 1
            10    9  11 2
            11    9  12 2
            12    1  13 1
            13   13  14 1
            14   13  15 2
            15   13  16 2

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Ontology (3)   
   KEGG BRITE (3)   
Drug (2)   
   KEGG DGROUP (1)   
   LigandBox (1)   
Chemical substance (6)   
   KEGG COMPOUND (1)   
   PubChem (1)   
   ChEBI (1)   
   HMDB (1)   
   HSDB (1)   
   NIKKAJI (1)   
All databases (11)   

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