KEGG   DRUG: Droxicam
Entry
D07267                      Drug                                   
Name
Droxicam (INN)
Formula
C16H11N3O5S
Exact mass
357.0419
Mol weight
357.3406
Structure
Simcomp
Class
Anti-inflammatory
 DG01504  Nonsteroidal anti-inflammatory drug (NSAID)
  DG01910  Anti-inflammatory drug, oxicams
Remark
ATC code: M01AC04
Efficacy
Anti-inflammatory, COX inhibitor
Comment
Oxicams
Nonsteroidal anti-inflammatory drug (NSAID)
Target
PTGS1 (COX1) [HSA:5742] [KO:K00509]
PTGS2 (COX2) [HSA:5743] [KO:K11987]
  Pathway
hsa00590  Arachidonic acid metabolism
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
   M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
    M01AC Oxicams
     M01AC04 Droxicam
      D07267  Droxicam (INN)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01504  Nonsteroidal anti-inflammatory drug (NSAID)
   DG01910  Anti-inflammatory drug, oxicams
    D07267  Droxicam
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Prostaglandin synthase
    PTGS1 (COX1)
     D07267  Droxicam (INN)
    PTGS2 (COX2)
     D07267  Droxicam (INN)
Other DBs
CAS: 90101-16-9
PubChem: 51091605
ChEBI: 76133
LigandBox: D07267
NIKKAJI: J25.832F
KCF data

ATOM        25
            1   C8x C    15.1900  -18.0600
            2   C8x C    15.1900  -19.4600
            3   C8x C    16.4024  -20.1600
            4   C8y C    17.6149  -19.4600
            5   C8y C    17.6149  -18.0600
            6   C8x C    16.4024  -17.3600
            7   S2x S    18.8273  -20.1600
            8   N4y N    20.0397  -19.4600
            9   C8y C    20.0397  -18.0600
            10  C8y C    18.8273  -17.3600
            11  C8y C    21.2522  -17.3600
            12  N4y N    21.2522  -15.9600
            13  C8y C    20.0397  -15.2600
            14  O7x O    18.8273  -15.9600
            15  C8y C    22.4853  -15.2478
            16  C8x C    23.6915  -15.9440
            17  C8x C    24.9039  -15.2439
            18  C8x C    24.9037  -13.8439
            19  C8x C    23.6975  -13.1477
            20  N5x N    22.4852  -13.8478
            21  O6a O    20.0397  -13.8601
            22  O3c O    17.8374  -21.1499
            23  O3c O    19.8173  -21.1499
            24  C1a C    21.2373  -20.1515
            25  O5x O    22.4853  -18.0722
BOND        28
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   12  15 1
            18   15  16 2
            19   16  17 1
            20   17  18 2
            21   18  19 1
            22   19  20 2
            23   15  20 1
            24   13  21 2
            25    7  22 2
            26    7  23 2
            27    8  24 1
            28   11  25 2

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Ontology (3)   
   KEGG BRITE (3)   
Drug (2)   
   KEGG DGROUP (1)   
   LigandBox (1)   
Chemical substance (3)   
   PubChem (1)   
   ChEBI (1)   
   NIKKAJI (1)   
Gene (4)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (2)   
All databases (12)   

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