| Entry |
|
|---|
| Name |
Chlorphenamine (INN);
Chlorpheniramine;
Clofeniramina (TN) |
|---|
| Formula |
C16H19ClN2
|
|---|
| Exact mass |
274.1237
|
|---|
| Mol weight |
274.7885
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
| Product (DG01099): | D00665<JP> |
| Product (mixture): | D11075<US> |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AB Substituted alkylamines
R06AB04 Chlorphenamine
D07398 Chlorphenamine (INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for integumentary system
57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
D07398 Chlorphenamine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Chlorphenamine
D07398 Chlorphenamine (INN)
Third-class OTC drugs
Inorganic and organic chemicals
Chlorphenamine
D07398 Chlorphenamine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01099 Chlorphenamine
D07398 Chlorphenamine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D07398 Chlorphenamine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01099 Chlorphenamine
|
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| Other DBs |
|
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| KCF data |
ATOM 19
1 C8x C 13.8600 -15.8900
2 C8y C 13.8600 -17.2900
3 C8x C 15.0724 -17.9900
4 C8x C 16.2849 -17.2900
5 C8y C 16.2849 -15.8900
6 C8x C 15.0724 -15.1900
7 C1c C 17.5160 -15.1790
8 C8y C 18.7212 -15.8747
9 C8x C 18.7216 -17.2896
10 C8x C 19.9342 -17.9893
11 C8x C 21.1465 -17.2889
12 C8x C 21.1460 -15.8739
13 N5x N 19.9334 -15.1743
14 C1b C 17.5157 -13.7901
15 C1b C 18.7281 -13.0901
16 N1c N 18.7281 -11.6901
17 C1a C 19.9643 -10.9760
18 C1a C 17.5397 -11.0038
19 X Cl 12.6476 -17.9900
BOND 20
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 8 13 1
15 7 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 16 18 1
20 2 19 1
|
|---|
