| Entry |
|
|---|
| Name |
Adomiparin (USAN);
Semuloparin (USAN);
Heparin (BAN);
Enoxaparin;
Bemiparin;
Parnaparin;
Nadroparin;
Heparin (TN) |
|---|
| Formula |
(C26H40N2O36S5)n
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Blood modifier agent
DG01950 Antithrombotic agent
DG01709 Heparin anticoagulant
|
|---|
| Remark |
| Product (DG00150): | D02112<JP/US> D04427<JP> D03674<JP/US> D04977<JP> D03353<JP/US> |
|
|---|
| Efficacy |
Anticoagulant, Antithrombin III activator, Platelet aggregation inhibitor |
|---|
| Comment |
Low molecular weight heparin (LMWH)
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04610 | Complement and coagulation cascades |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B01 ANTITHROMBOTIC AGENTS
B01A ANTITHROMBOTIC AGENTS
B01AB Heparin group
B01AB01 Heparin
D07510 Adomiparin (USAN)
B01AB12 Bemiparin
D07510 Adomiparin (USAN)
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05B ANTIVARICOSE THERAPY
C05BA Heparins or heparinoids for topical use
C05BA03 Heparin
D07510 Adomiparin (USAN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01X OTHER OPHTHALMOLOGICALS
S01XA Other ophthalmologicals
S01XA14 Heparin
D07510 Adomiparin (USAN)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01709 Heparin anticoagulant
DG00150 Heparin
D07510 Adomiparin
Target-based classification of drugs [BR:br08310]
Not elsewhere classified
Organismal systems
Complement and coagulation
SERPINC1 (AT3)
D07510 Adomiparin (USAN)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01709 Heparin anticoagulant
DG00150 Heparin
|
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| Other DBs |
|
|---|
| KCF data |
ATOM 71
1 C1y C 20.6500 -19.0400
2 C1y C 21.7700 -19.6700
3 C1y C 20.6500 -17.7100
4 O2a O 19.0400 -19.9500
5 C1y C 22.8900 -19.0400
6 O2a O 21.7700 -21.0000
7 O2x O 21.7700 -17.0800
8 C1b C 19.4600 -17.0800
9 C1y C 17.3600 -20.8600
10 C1y C 22.8900 -17.7100
11 N1b N 23.9400 -20.2300
12 O1a O 18.3400 -17.7100
13 C1y C 17.3600 -22.1900
14 O2x O 16.2400 -20.2300
15 O2a O 24.5000 -16.8000
16 S4a S 25.9000 -20.2300
17 C1y C 16.2400 -22.8900
18 O2a O 18.9000 -23.8000
19 C1y C 15.1200 -20.8600
20 C1y C 26.1800 -15.8200
21 O1d O 25.9000 -21.5600
22 O1d O 25.9000 -18.9000
23 O1d O 27.2300 -20.2300
24 C1y C 15.1200 -22.1900
25 O1a O 16.2400 -24.1500
26 C6a C 14.0000 -20.2300
27 C1y C 26.1800 -14.4900
28 C1y C 27.3000 -16.5200
29 O1a O 13.9300 -22.8900
30 O6a O 12.8100 -20.8600
31 O6a O 14.0000 -18.9000
32 O2x O 27.3000 -13.8600
33 C6a C 24.9900 -13.8600
34 C1y C 28.4200 -15.8200
35 O1a O 27.3000 -17.7800
36 Z * 11.1300 -22.8200
37 C1y C 28.4200 -14.4900
38 O6a O 23.8700 -14.4900
39 O6a O 24.9900 -12.5300
40 O2a O 30.8700 -17.2900
41 O2a O 30.0300 -13.5800
42 C1y C 31.7100 -12.6000
43 C1y C 31.7100 -11.3400
44 C1y C 32.8300 -13.3000
45 O2x O 32.8300 -10.6400
46 C1b C 30.5200 -10.6400
47 C1y C 33.9500 -12.6000
48 O1a O 32.8300 -14.6300
49 C1x C 33.9500 -11.3400
50 O2a O 29.2600 -10.6400
51 N1b N 35.9800 -13.5800
52 Z * 36.4000 -9.9400
53 S4a S 27.9300 -10.6400
54 C5a C 35.9800 -14.9100
55 O1d O 27.9300 -11.9700
56 O1d O 27.9300 -9.3100
57 O1d O 26.6000 -10.6400
58 C1a C 37.1700 -15.5400
59 O5a O 34.8600 -15.5400
60 S4a S 18.9000 -25.2000
61 O1d O 18.9000 -26.6000
62 O1d O 20.3000 -25.2000
63 O1d O 17.5000 -25.2000
64 S4a S 21.7700 -22.4000
65 O1d O 21.7700 -23.8000
66 O1d O 23.1700 -22.4000
67 O1d O 20.3700 -22.4000
68 S4a S 30.8700 -18.6900
69 O1d O 30.8700 -20.0900
70 O1d O 32.2700 -18.6900
71 O1d O 29.4700 -18.6900
BOND 74
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 2 5 1
5 2 6 1 #Up
6 3 7 1
7 3 8 1 #Up
8 9 4 1 #Up
9 5 10 1
10 5 11 1 #Down
11 8 12 1
12 9 13 1
13 9 14 1
14 10 15 1 #Down
15 11 16 1
16 13 17 1
17 13 18 1 #Down
18 14 19 1
19 20 15 1 #Down
20 16 21 1
21 16 22 2
22 16 23 2
23 17 24 1
24 17 25 1 #Up
25 19 26 1 #Down
26 20 27 1
27 20 28 1
28 24 29 1 #Down
29 26 30 1
30 26 31 2
31 27 32 1
32 27 33 1 #Up
33 28 34 1
34 28 35 1 #Up
35 29 36 1
36 32 37 1
37 33 38 1
38 33 39 2
39 34 40 1 #Down
40 37 41 1 #Up
41 42 41 1 #Down
42 42 43 1
43 42 44 1
44 43 45 1
45 43 46 1 #Up
46 44 47 1
47 44 48 1 #Up
48 45 49 1
49 46 50 1
50 47 51 1 #Down
51 49 52 1
52 50 53 1
53 51 54 1
54 53 55 1
55 53 56 2
56 53 57 2
57 54 58 1
58 54 59 2
59 7 10 1
60 19 24 1
61 34 37 1
62 47 49 1
63 18 60 1
64 60 61 2
65 60 62 2
66 60 63 1
67 6 64 1
68 64 65 2
69 64 66 2
70 64 67 1
71 40 68 1
72 68 69 2
73 68 70 2
74 68 71 1
BRACKET 1 12.3900 -23.4500 12.3900 -22.1200
1 35.0000 -9.9400 35.0000 -11.2700
1 n
ORIGINAL 1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
1 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32
1 33 34 35 37 38 39 40 41 42 43 44 45 46 47 48 49
1 50 51 53 54 55 56 57 58 59 60 61 62 63 64 65 66
1 67 68 69 70 71
REPEAT 1
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|---|
