| Entry |
|
|---|
| Name |
Betahistine (INN);
Vestibo (TN) |
|---|
| Formula |
C8H12N2
|
|---|
| Exact mass |
136.1
|
|---|
| Mol weight |
136.1943
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01556 Histamine receptor H3 antagonist
|
|---|
| Remark |
| Product (DG01004): | D01592<JP> |
|
|---|
| Efficacy |
Antivertigo, Vasodilator, Antihistaminic |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07C ANTIVERTIGO PREPARATIONS
N07CA Antivertigo preparations
N07CA01 Betahistine
D07522 Betahistine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01556 Histamine receptor H3 antagonist
DG01004 Betahistine
D07522 Betahistine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D07522 Betahistine (INN)
HRH3
D07522 Betahistine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01556 Histamine receptor H3 antagonist
DG01004 Betahistine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 10
1 C8x C 27.7900 -18.6200
2 C8x C 27.7900 -17.2200
3 N5x N 26.5300 -16.5200
4 C8y C 25.3400 -17.2200
5 C8x C 25.3400 -18.6200
6 C8x C 26.5300 -19.3200
7 C1b C 24.1500 -16.5200
8 C1b C 22.8900 -17.2200
9 N1b N 21.7000 -16.5200
10 C1a C 20.5100 -17.2200
BOND 10
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 6 1 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
|
|---|
