| Entry |
|
|---|
| Name |
Brimonidine (INN) |
|---|
| Formula |
C11H10BrN5
|
|---|
| Exact mass |
291.012
|
|---|
| Mol weight |
292.1346
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
| Product (DG00442): | D02076<JP/US> |
|
|---|
| Efficacy |
Antiglaucoma, alpha2-Adrenergic receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D11 OTHER DERMATOLOGICAL PREPARATIONS
D11A OTHER DERMATOLOGICAL PREPARATIONS
D11AX Other dermatologicals
D11AX21 Brimonidine
D07540 Brimonidine (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EA Sympathomimetics in glaucoma therapy
S01EA05 Brimonidine
D07540 Brimonidine (INN)
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA07 Brimonidine
D07540 Brimonidine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG00442 Brimonidine
D07540 Brimonidine
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG00442 Brimonidine
D07540 Brimonidine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA2
D07540 Brimonidine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG00442 Brimonidine
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG00442 Brimonidine
|
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| Other DBs |
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|---|
| KCF data |
ATOM 17
1 C8x C 16.3100 -16.7300
2 C8x C 16.3100 -18.1300
3 N5x N 17.5000 -18.8300
4 C8y C 18.7600 -18.1300
5 C8y C 18.7600 -16.7300
6 N5x N 17.5000 -16.0300
7 C8x C 19.9500 -18.8300
8 C8x C 21.1400 -18.1300
9 C8y C 21.1400 -16.7300
10 C8y C 19.9500 -16.0300
11 N2x N 23.5900 -18.1300
12 C2y C 23.5900 -16.7300
13 N1b N 22.4000 -16.0300
14 C1x C 24.9200 -18.5500
15 C1x C 25.7600 -17.4300
16 N1x N 24.9200 -16.3100
17 X Br 19.9500 -14.6300
BOND 19
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 5 10 1
12 11 12 2
13 12 13 1
14 9 13 1
15 11 14 1
16 14 15 1
17 15 16 1
18 12 16 1
19 10 17 1
|
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