| Entry |
|
|---|
| Name |
Brompheniramine (INN);
Brotane (TN) |
|---|
| Formula |
C16H19BrN2
|
|---|
| Exact mass |
318.0732
|
|---|
| Mol weight |
319.2395
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
| Product (mixture): | D11647<US> |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AB Substituted alkylamines
R06AB01 Brompheniramine
D07543 Brompheniramine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01097 Brompheniramine
D07543 Brompheniramine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D07543 Brompheniramine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01097 Brompheniramine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 19
1 C1c C 24.7800 -18.6900
2 C8y C 23.5200 -19.3900
3 C8y C 25.9700 -19.3900
4 C1b C 24.7800 -17.2900
5 C8x C 22.3300 -18.6900
6 C8x C 23.5200 -20.7900
7 C8x C 25.9700 -20.7900
8 N5x N 27.1600 -18.6200
9 C1b C 25.9700 -16.5900
10 C8x C 21.1400 -19.3900
11 C8x C 22.3300 -21.4900
12 C8x C 27.1600 -21.4900
13 C8x C 28.4200 -19.3900
14 N1c N 25.9700 -15.1900
15 C8y C 21.1400 -20.7900
16 C8x C 28.4200 -20.7900
17 C1a C 24.7100 -14.4900
18 C1a C 27.1600 -14.4200
19 X Br 19.9500 -21.4900
BOND 20
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 2
6 3 7 1
7 3 8 2
8 4 9 1
9 5 10 2
10 6 11 1
11 7 12 2
12 8 13 1
13 9 14 1
14 10 15 1
15 12 16 1
16 14 17 1
17 14 18 1
18 15 19 1
19 11 15 2
20 13 16 2
|
|---|
