| Entry |
|
|---|
| Name |
Bupropion (INN) |
|---|
| Formula |
C13H18ClNO
|
|---|
| Exact mass |
239.1077
|
|---|
| Mol weight |
239.7411
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI)
|
|---|
| Remark |
| Product (DG00957): | D00817<US> D07938<US> |
| Product (mixture): | D10751<US> |
|
|---|
| Efficacy |
Antidepressant, Noradrenalin and dopamine reuptake inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AX Other antidepressants
N06AX12 Bupropion
D07591 Bupropion (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI)
DG00957 Bupropion
D07591 Bupropion
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D07591 Bupropion (INN)
SLC6A3 (DAT1)
D07591 Bupropion (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI)
DG00957 Bupropion
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 16
1 C8y C 17.4300 -16.1700
2 C5a C 18.6200 -15.4700
3 C8x C 16.1700 -15.4700
4 C8x C 17.4300 -17.5700
5 C1c C 19.8100 -16.1700
6 O5a O 18.6200 -14.0700
7 C8y C 14.9800 -16.1700
8 C8x C 16.1700 -18.2700
9 N1b N 21.0000 -15.4700
10 C1a C 19.8100 -17.5700
11 C8x C 14.9800 -17.5700
12 X Cl 13.7900 -15.4700
13 C1d C 22.2600 -16.1700
14 C1a C 23.4500 -15.4700
15 C1a C 22.2600 -17.5700
16 C1a C 23.4500 -16.9400
BOND 16
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 2 6 2
6 3 7 1
7 4 8 2
8 5 9 1
9 5 10 1
10 7 11 2
11 7 12 1
12 9 13 1
13 13 14 1
14 13 15 1
15 13 16 1
16 8 11 1
|
|---|
