| Entry |
|
|---|
| Name |
Butenafine (INN) |
|---|
| Formula |
C23H27N
|
|---|
| Exact mass |
317.2144
|
|---|
| Mol weight |
317.4672
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
| Product (DG00378): | D01093<JP> |
|
|---|
| Efficacy |
Antifungal, Ergosterol biosynthesis inhibitor |
|---|
| Comment |
Benzylamine derivative
|
|---|
| Target |
squalene epoxidase [KO: K00511] |
|---|
| Pathway |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
D01A ANTIFUNGALS FOR TOPICAL USE
D01AE Other antifungals for topical use
D01AE23 Butenafine
D07596 Butenafine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Butenafine
D07596 Butenafine (INN)
Second-class OTC drugs
Inorganic and organic chemicals
Butenafine
D07596 Butenafine (INN)
Antimicrobials [BR:br08307]
Antifungals
Ergosterol biosynthesis inhibitor
Other ergosterol biosynthesis inhibitor
D07596 Butenafine (INN)
|
|---|
| Other DBs |
|
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| KCF data |
ATOM 24
1 C8x C 14.0000 -18.9000
2 C8x C 14.0000 -20.3000
3 C8x C 15.2124 -21.0000
4 C8y C 16.4249 -20.3000
5 C8y C 16.4249 -18.9000
6 C8x C 15.2124 -18.2000
7 C8x C 17.6373 -21.0000
8 C8x C 18.8497 -20.3000
9 C8x C 18.8497 -18.9000
10 C8y C 17.6373 -18.2000
11 C1b C 17.6373 -16.8000
12 N1c N 18.8518 -16.0988
13 C1b C 20.0483 -16.7898
14 C8y C 21.2351 -16.1046
15 C8x C 22.4266 -16.7928
16 C8x C 23.6391 -16.0929
17 C8y C 23.6393 -14.6929
18 C8x C 22.4478 -14.0048
19 C8x C 21.2353 -14.7046
20 C1d C 24.8641 -13.9858
21 C1a C 26.0766 -13.2858
22 C1a C 25.5667 -15.2026
23 C1a C 24.1668 -12.7780
24 C1a C 18.8518 -14.7002
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 5 10 1
12 10 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 14 19 1
22 17 20 1
23 20 21 1
24 20 22 1
25 20 23 1
26 12 24 1
|
|---|
