| Entry |
|
|---|
| Name |
Carbinoxamine (INN) |
|---|
| Formula |
C16H19ClN2O
|
|---|
| Exact mass |
290.1186
|
|---|
| Mol weight |
290.7879
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
| Product (DG01095): | D01336<US> |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA08 Carbinoxamine
D07617 Carbinoxamine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Carbinoxamine
D07617 Carbinoxamine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01095 Carbinoxamine
D07617 Carbinoxamine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D07617 Carbinoxamine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01095 Carbinoxamine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 20
1 C8x C 27.7900 -18.9700
2 C8x C 27.7900 -20.3700
3 C8x C 26.6000 -21.0700
4 C8x C 25.3400 -20.3700
5 C8y C 25.3400 -18.9700
6 N5x N 26.6000 -18.2700
7 C8x C 22.9600 -20.3700
8 C8y C 22.9600 -18.9700
9 C1c C 24.1500 -18.2700
10 C8x C 21.7000 -21.0700
11 C8y C 20.5100 -20.3700
12 C8x C 20.5100 -18.9700
13 C8x C 21.7000 -18.2700
14 X Cl 19.3200 -21.0700
15 O2a O 24.1500 -16.8700
16 C1b C 25.4100 -16.1700
17 C1b C 26.6000 -16.8700
18 N1c N 27.7900 -16.1700
19 C1a C 28.9800 -16.8700
20 C1a C 27.7900 -14.7700
BOND 21
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 1
8 8 9 1
9 5 9 1
10 7 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 8 13 2
15 11 14 1
16 9 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 18 20 1
|
|---|
