| Entry |
|
|---|
| Name |
Cyproheptadine (INN);
Ciprovit (TN) |
|---|
| Formula |
C21H21N
|
|---|
| Exact mass |
287.1674
|
|---|
| Mol weight |
287.3981
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
| Product (DG01109): | D02234<JP/US> |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AX Other antihistamines for systemic use
R06AX02 Cyproheptadine
D07765 Cyproheptadine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01109 Cyproheptadine
D07765 Cyproheptadine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D07765 Cyproheptadine (INN)
Serotonin
HTR1
D07765 Cyproheptadine (INN)
HTR2
D07765 Cyproheptadine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01109 Cyproheptadine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 22
1 C2x C 23.4500 -22.2600
2 C8y C 22.6100 -21.1400
3 C8y C 22.8900 -19.7400
4 C2y C 24.1500 -19.1800
5 C2x C 24.8500 -22.2600
6 C8y C 25.4100 -19.8100
7 C8y C 25.7600 -21.2100
8 C8x C 21.8400 -18.7600
9 C8x C 20.5100 -19.1800
10 C8x C 20.1600 -20.5100
11 C8x C 21.1400 -21.4900
12 C8x C 27.0900 -21.6300
13 C8x C 28.1400 -20.6500
14 C8x C 27.7900 -19.3200
15 C8x C 26.4600 -18.9000
16 C2y C 24.1500 -17.7800
17 C1x C 25.3400 -17.0800
18 C1x C 25.3400 -15.6800
19 N1y N 24.1500 -14.9800
20 C1x C 22.9600 -15.6800
21 C1x C 22.9600 -17.0800
22 C1a C 24.1500 -13.5800
BOND 25
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 2
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 16 21 1
25 19 22 1
|
|---|
