| Entry |
|
|---|
| Name |
Desoxycortone (INN);
Desoxycorticosterone |
|---|
| Formula |
C21H30O3
|
|---|
| Exact mass |
330.2195
|
|---|
| Mol weight |
330.4611
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
|
|---|
| Efficacy |
Salts metabolic regulator, Mineralocorticoid receptor agonist |
|---|
| Comment |
Adrenal cortex hormone
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04960 | Aldosterone-regulated sodium reabsorption |
|
|---|
| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AA Mineralocorticoids
H02AA03 Desoxycortone
D07792 Desoxycortone (INN)
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C2 (MR)
D07792 Desoxycortone (INN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 24
1 C1y C 27.9338 -19.0427
2 C1y C 26.7436 -19.7428
3 C1z C 27.9338 -17.6425
4 C1y C 25.5534 -19.0427
5 C1x C 26.7436 -21.1430
6 C1x C 26.7436 -16.9424
7 C1z C 24.2933 -19.7428
8 C1x C 25.5534 -17.6425
9 C1x C 25.4834 -21.8432
10 C2y C 24.2933 -21.1430
11 C1x C 23.1031 -19.0427
12 C1a C 24.2933 -18.3426
13 C2x C 23.1031 -21.8432
14 C1x C 21.9129 -19.7428
15 C5x C 21.9129 -21.1430
16 O5x O 20.6527 -21.8432
17 C1x C 30.3587 -19.0428
18 C1x C 30.3587 -17.6426
19 C1y C 29.1462 -16.9425
20 C5a C 29.1463 -15.5402
21 C1b C 30.3390 -14.8515
22 O5a O 27.9142 -14.8287
23 O1a O 31.5247 -15.5360
24 C1a C 27.9322 -16.2400
BOND 27
1 1 2 1
2 1 3 1
3 2 4 1
4 2 5 1
5 3 6 1
6 4 7 1
7 4 8 1
8 5 9 1
9 7 10 1
10 7 11 1
11 7 12 1 #Up
12 10 13 2
13 11 14 1
14 13 15 1
15 15 16 2
16 6 8 1
17 9 10 1
18 14 15 1
19 1 17 1
20 17 18 1
21 18 19 1
22 3 19 1
23 19 20 1 #Up
24 20 21 1
25 20 22 2
26 21 23 1
27 3 24 1 #Up
|
|---|
