| Entry |
|
|---|
| Name |
Dextropropoxyphene (INN);
Propoxypene |
|---|
| Formula |
C22H29NO2
|
|---|
| Exact mass |
339.2198
|
|---|
| Mol weight |
339.4712
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
|
|---|
| Remark |
| Product (DG00818): | D00482<US> |
|
|---|
| Efficacy |
Analgesic, Opioid receptor agonist |
|---|
| Comment |
Diphenylpropylamine derivative
semi-synthetic opioids
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AC Diphenylpropylamine derivatives
N02AC04 Dextropropoxyphene
D07809 Dextropropoxyphene (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00818 Dextropropoxyphene
D07809 Dextropropoxyphene
Analgesic
DG01984 Opioid analgesics
DG00818 Dextropropoxyphene
D07809 Dextropropoxyphene
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D07809 Dextropropoxyphene (INN)
Narcotics and psychotropics in Japan [br08308.html]
Narcotics by Control Act Article 2 Table 1 (74 substances)
D07809
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00818 Dextropropoxyphene
Analgesic
DG01984 Opioid analgesics
DG00818 Dextropropoxyphene
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 25
1 C8x C 15.7997 -19.1502
2 C8x C 16.4991 -20.4090
3 C8x C 17.8977 -20.4090
4 C8x C 18.5970 -19.1502
5 C8y C 17.8977 -17.9613
6 C8x C 16.4991 -17.9613
7 C8x C 19.9957 -19.1502
8 C8y C 20.6950 -17.9613
9 C1b C 19.9957 -16.7726
10 C1d C 18.5970 -16.7726
11 C8x C 20.6950 -20.4090
12 C8x C 22.0937 -20.4090
13 C8x C 22.7930 -19.1502
14 C8x C 22.0937 -17.9613
15 O7a O 17.8977 -15.5837
16 C7a C 16.4991 -15.5837
17 C1b C 15.7997 -14.3949
18 C1a C 14.4011 -14.3949
19 O6a O 15.7997 -16.7726
20 C1c C 19.2964 -15.5138
21 C1a C 20.6950 -15.5138
22 C1b C 18.5970 -14.3249
23 N1c N 19.2964 -13.1361
24 C1a C 20.6950 -13.1361
25 C1a C 18.5970 -11.8773
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 1
8 8 9 1
9 10 9 1 #Down
10 10 5 1 #Up
11 7 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 8 14 2
16 10 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 16 19 2
21 10 20 1
22 20 21 1 #Up
23 20 22 1
24 22 23 1
25 23 24 1
26 23 25 1
|
|---|
