| Entry |
|
|---|
| Name |
Diphenylpyraline (INN) |
|---|
| Formula |
C19H23NO
|
|---|
| Exact mass |
281.178
|
|---|
| Mol weight |
281.392
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
Respiratory system agent
DG01616 Xanthine derivative
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA07 Diphenylpyraline
D07862 Diphenylpyraline (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Diphenylpyraline
D07862 Diphenylpyraline (INN)
Third-class OTC drugs
Inorganic and organic chemicals
Diphenylpyraline
D07862 Diphenylpyraline (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01094 Diphenylpyraline
D07862 Diphenylpyraline
Respiratory system agent
DG01616 Xanthine derivative
DG01094 Diphenylpyraline
D07862 Diphenylpyraline
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D07862 Diphenylpyraline (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01094 Diphenylpyraline
Respiratory system agent
DG01616 Xanthine derivative
DG01094 Diphenylpyraline
|
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| Other DBs |
|
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| KCF data |
ATOM 21
1 C8x C 19.9500 -19.3200
2 C8x C 19.9500 -20.7200
3 C8x C 21.1400 -21.4200
4 C8x C 22.4000 -20.7200
5 C8y C 22.4000 -19.3200
6 C8x C 21.1400 -18.6200
7 C1c C 23.5900 -18.6200
8 C8y C 24.7800 -19.3200
9 O2a O 23.5900 -17.2200
10 C8x C 24.7800 -20.7200
11 C8x C 26.0400 -21.4200
12 C8x C 27.2300 -20.7200
13 C8x C 27.2300 -19.3200
14 C8x C 26.0400 -18.6200
15 C1y C 24.7800 -16.5200
16 C1x C 26.0400 -17.2200
17 C1x C 27.2300 -16.5200
18 N1y N 27.2300 -15.1200
19 C1x C 26.0400 -14.4200
20 C1x C 24.7800 -15.1200
21 C1a C 28.4200 -14.4200
BOND 23
1 4 5 1
2 5 6 2
3 6 1 1
4 8 10 2
5 10 11 1
6 11 12 2
7 12 13 1
8 13 14 2
9 14 8 1
10 9 15 1
11 5 7 1
12 7 8 1
13 1 2 2
14 7 9 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 15 1
21 2 3 1
22 18 21 1
23 3 4 2
|
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