| Entry |
|
|---|
| Name |
Diprenorphine (INN) |
|---|
| Formula |
C26H35NO4
|
|---|
| Exact mass |
425.2566
|
|---|
| Mol weight |
425.5604
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Analgesic
DG01587 Opioid receptor agonist/antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidote, Narcotic antagonist, Opioid receptor agonist/antagonist |
|---|
| Comment |
Morphinan derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Analgesic
DG01587 Opioid receptor agonist/antagonist
DG01273 Diprenorphine
D07863 Diprenorphine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D07863 Diprenorphine (INN)
OPRK1
D07863 Diprenorphine (INN)
Drug groups [BR:br08330]
Analgesic
DG01587 Opioid receptor agonist/antagonist
DG01273 Diprenorphine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 31
1 C1z C 20.6500 -21.7700
2 C1z C 21.8400 -22.4700
3 C1y C 19.4600 -22.4700
4 C8y C 20.6500 -20.4400
5 C1x C 21.8400 -21.0700
6 C1y C 23.0300 -21.7700
7 C1x C 21.8400 -23.8700
8 C1x C 21.2800 -23.5200
9 C1z C 19.4600 -23.8000
10 O2x O 18.8300 -20.9300
11 C8y C 19.5300 -19.7400
12 C8y C 21.9100 -19.7400
13 C1x C 24.2200 -21.0700
14 N1y N 24.2200 -22.4700
15 C1x C 23.1000 -20.4400
16 C1y C 20.6500 -24.5000
17 C1x C 20.0900 -22.8200
18 C8y C 19.5300 -18.3400
19 C8x C 21.9100 -18.3400
20 C1b C 25.4100 -21.8400
21 C8x C 20.7200 -17.6400
22 O1a O 18.3400 -17.6400
23 C1y C 26.6000 -22.5400
24 C1x C 27.3000 -23.7300
25 C1x C 28.0000 -22.5400
26 C1d C 21.3500 -25.6900
27 C1a C 22.7500 -25.6900
28 C1a C 20.6500 -26.8800
29 O1a O 22.0500 -26.8800
30 C1a C 17.0800 -23.8000
31 O2a O 18.2700 -24.5000
BOND 37
1 1 5 1 #Up
2 2 6 1
3 2 7 1
4 2 8 1 #Down
5 3 9 1
6 3 10 1 #Down
7 4 11 1
8 4 12 2
9 5 13 1
10 6 14 1 #Up
11 6 15 1
12 7 16 1
13 8 17 1
14 11 18 2
15 12 19 1
16 14 20 1
17 18 21 1
18 18 22 1
19 9 16 1
20 9 17 1 #Down
21 10 11 1
22 12 15 1
23 14 13 1 #Up
24 19 21 2
25 1 2 1
26 20 23 1
27 1 3 1
28 1 4 1
29 23 24 1
30 23 25 1
31 25 24 1
32 16 26 1
33 26 27 1
34 26 28 1
35 26 29 1
36 30 31 1
37 31 9 1
|
|---|
