| Entry |
|
|---|
| Name |
Doxycycline (INN);
Doxychel (TN);
Doxycycline (TN) |
|---|
| Formula |
C22H24N2O8
|
|---|
| Exact mass |
444.1533
|
|---|
| Mol weight |
444.4346
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01197 Tetracycline antibiotic
|
|---|
| Remark |
| Product (DG00008): | D00307<US> D02129<JP/US> |
|
|---|
| Efficacy |
Antibiotic, Protein biosynthesis inhibitor |
|---|
| Target |
30S ribosomal subunit |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AB Antiinfectives and antiseptics for local oral treatment
A01AB22 Doxycycline
D07876 Doxycycline (INN)
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01A TETRACYCLINES
J01AA Tetracyclines
J01AA02 Doxycycline
D07876 Doxycycline (INN)
Drug groups [BR:br08330]
Antibacterial
DG01197 Tetracycline antibiotic
DG00008 Doxycycline
D07876 Doxycycline
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Tetracycline
D07876 Doxycycline (INN)
Drug groups [BR:br08330]
Antibacterial
DG01197 Tetracycline antibiotic
DG00008 Doxycycline
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Tetracycline
DG00008 Doxycycline
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 32
1 C1y C 25.3288 -17.9821
2 C1z C 25.3288 -19.3115
3 C1y C 26.5183 -17.3524
4 C1y C 24.1394 -17.2824
5 C2y C 24.1394 -20.0112
6 C5x C 26.4483 -20.0112
7 C2y C 27.6378 -18.0520
8 C1y C 23.0199 -17.9821
9 C2y C 23.0199 -19.3115
10 O1a O 24.1394 -21.3406
11 C2y C 27.6378 -19.3815
12 O5x O 26.4483 -21.4106
13 O1a O 28.8273 -17.3524
14 C1y C 21.8304 -17.2824
15 C5x C 21.8304 -20.0112
16 C5a C 28.8273 -20.0811
17 C8y C 20.6409 -17.9821
18 C8y C 20.6409 -19.3115
19 O5x O 21.8304 -21.3406
20 N1a N 30.0168 -19.3815
21 O5a O 28.8273 -21.4106
22 C8x C 19.4514 -17.2824
23 C8y C 19.4514 -20.0112
24 C8x C 18.2620 -17.9821
25 C8x C 18.2620 -19.3115
26 O1a O 19.4514 -21.3406
27 C1a C 21.8304 -15.6031
28 N1c N 26.5183 -15.1133
29 C1a C 27.7078 -14.4836
30 C1a C 25.3288 -14.4136
31 O1a O 24.1394 -15.6031
32 O1a O 25.3288 -20.7109
BOND 35
1 5 9 2
2 5 10 1
3 6 11 1
4 6 12 2
5 7 13 1
6 8 14 1
7 9 15 1
8 11 16 1
9 14 17 1
10 15 18 1
11 15 19 2
12 16 20 1
13 16 21 2
14 17 22 1
15 18 23 1
16 22 24 2
17 23 25 2
18 23 26 1
19 7 11 2
20 8 9 1
21 17 18 2
22 24 25 1
23 14 27 1 #Down
24 3 28 1 #Down
25 1 2 1
26 28 29 1
27 1 3 1
28 28 30 1
29 1 4 1
30 2 5 1
31 2 6 1
32 4 31 1 #Down
33 3 7 1
34 2 32 1 #Down
35 4 8 1
|
|---|
