| Entry |
|
|---|
| Name |
Imidapril (INN);
Hipertene (TN) |
|---|
| Formula |
C20H27N3O6
|
|---|
| Exact mass |
405.19
|
|---|
| Mol weight |
405.4449
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
|
|---|
| Remark |
| Product (DG00347): | D01549<JP> |
|
|---|
| Efficacy |
Antihypertensive, Angiotensin-converting enzyme inhibitor |
|---|
| Comment |
Active form of prodrug: Imidaprilat [CPD: C21519]
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07217 | Renin-angiotensin system inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09A ACE INHIBITORS, PLAIN
C09AA ACE inhibitors, plain
C09AA16 Imidapril
D08068 Imidapril (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00347 Imidapril
D08068 Imidapril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00347 Imidapril
D08068 Imidapril
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Peptidyl-dipeptidases
ACE (CD143)
D08068 Imidapril (INN)
Prodrugs [br08324.html]
D08068
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00347 Imidapril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00347 Imidapril
Prodrugs [br08324.html]
DG00347
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 29
1 C8x C 15.6800 -19.1100
2 C8x C 15.6800 -20.5100
3 C8x C 16.9400 -21.2100
4 C8x C 18.1300 -20.5100
5 C8y C 18.1300 -19.1100
6 C8x C 16.9400 -18.4100
7 C1b C 19.3900 -18.4100
8 C1b C 20.5800 -19.1100
9 C1c C 21.8400 -18.4100
10 N1b N 23.0300 -19.1100
11 C1c C 24.2200 -18.4100
12 C5a C 25.4800 -19.1100
13 N1y N 26.6700 -18.4100
14 C7a C 21.8400 -17.0100
15 C1a C 24.2200 -17.0100
16 O6a O 23.0300 -16.3100
17 O7a O 20.5800 -16.3100
18 C1b C 19.3900 -17.0100
19 C1a C 18.2000 -16.3100
20 O5a O 25.4800 -20.5100
21 C5x C 27.7900 -19.2500
22 N1y N 28.9100 -18.4100
23 C1x C 28.4900 -17.0800
24 C1y C 27.0900 -17.0800
25 O5x O 27.7900 -20.6500
26 C1a C 30.1000 -19.1100
27 O6a O 27.0900 -14.7000
28 C6a C 26.3900 -15.8900
29 O6a O 24.9900 -15.8900
BOND 30
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 9 14 1 #Up
15 11 15 1 #Up
16 14 16 2
17 14 17 1
18 17 18 1
19 18 19 1
20 12 20 2
21 13 21 1
22 21 22 1
23 22 23 1
24 23 24 1
25 13 24 1
26 21 25 2
27 22 26 1
28 27 28 1
29 24 28 1 #Down
30 28 29 2
|
|---|
