| Entry |
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| Name |
Leuprorelin (INN);
Enantone (TN) |
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| Formula |
C59H84N16O12
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| Exact mass |
1208.6455
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| Mol weight |
1209.3983
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| Structure |
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| Simcomp |
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| Class |
Hormonal agent
DG01494 Gonadotropin-releasing hormone receptor agonist
|
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| Remark |
| Product (DG00730): | D00989<JP/US> D12337<US> |
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| Efficacy |
Antineoplastic, Gonadotropin-releasing hormone receptor agonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L02 ENDOCRINE THERAPY
L02A HORMONES AND RELATED AGENTS
L02AE Gonadotropin releasing hormone analogues
L02AE02 Leuprorelin
D08113 Leuprorelin (INN)
Drug groups [BR:br08330]
Hormonal agent
DG01494 Gonadotropin-releasing hormone receptor agonist
DG00730 Leuprorelin
D08113 Leuprorelin
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Gonadotropin-releasing hormone
GNRHR
D08113 Leuprorelin (INN)
Drug groups [BR:br08330]
Hormonal agent
DG01494 Gonadotropin-releasing hormone receptor agonist
DG00730 Leuprorelin
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| Other DBs |
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| KCF data |
ATOM 87
1 C1c C 18.9597 -23.3717
2 N1b N 17.7703 -24.0014
3 C5a C 20.2190 -24.0014
4 C5a C 16.5809 -23.3717
5 N1b N 21.3384 -23.3018
6 O5a O 20.2190 -25.3307
7 C1c C 15.3916 -24.0714
8 O5a O 16.5809 -21.9025
9 C1c C 22.5277 -23.9314
10 N1b N 14.1323 -23.3717
11 C5a C 23.7871 -23.3018
12 C5a C 12.9429 -24.0714
13 N1b N 24.9764 -23.9314
14 O5a O 23.7871 -21.8326
15 C1y C 11.7536 -23.4417
16 O5a O 12.9429 -25.4706
17 C1c C 26.1658 -23.2318
18 C1x C 10.4942 -23.8615
19 N1x N 11.7536 -21.9725
20 C1b C 26.1658 -21.8326
21 C5a C 27.3551 -23.9314
22 C1x C 9.6547 -22.6721
23 C5x C 10.4942 -21.6227
24 C8y C 27.2852 -21.1329
25 N1b N 28.6145 -23.2318
26 O5a O 27.3551 -25.3307
27 O5x O 10.0045 -20.2934
28 C8x C 28.6145 -21.7626
29 C8x C 27.2852 -19.7337
30 C1c C 29.8738 -23.9314
31 C8x C 29.8038 -21.0630
32 C8x C 28.5445 -19.0341
33 C5a C 31.0631 -23.2318
34 C8y C 29.8038 -19.7337
35 N1b N 32.2525 -23.9314
36 O5a O 31.0631 -21.7626
37 O1a O 30.9232 -19.0341
38 C1c C 33.4419 -23.2318
39 C5a C 34.6312 -23.8615
40 N1b N 35.8206 -23.1619
41 O5a O 34.6312 -25.2607
42 C1c C 37.0099 -23.8615
43 C5a C 38.2693 -23.1619
44 C1b C 37.0099 -25.2607
45 N1y N 39.5286 -23.7915
46 O5a O 38.2693 -21.6926
47 C1y C 40.8579 -23.7915
48 C1x C 39.1088 -25.1208
49 C1x C 41.2776 -25.1208
50 C5a C 42.1871 -23.0919
51 C1x C 40.1582 -25.8904
52 N1b N 43.4465 -23.8615
53 O5a O 42.1871 -21.5527
54 C1b C 18.9597 -21.9025
55 C8y C 20.2889 -21.2729
56 C8y C 20.7087 -20.0136
57 C8x C 21.4083 -22.0425
58 C8y C 22.0380 -20.0136
59 C8x C 20.0091 -18.8242
60 N4x N 22.5277 -21.2729
61 C8x C 22.7376 -18.7542
62 C8x C 20.7087 -17.5649
63 C8x C 22.0380 -17.5649
64 C1b C 15.3916 -25.4706
65 C8y C 16.5809 -26.1702
66 C8x C 16.5809 -27.5695
67 N5x N 17.8403 -28.0592
68 C8x C 18.6798 -26.9398
69 N4x N 17.9802 -25.7505
70 C1b C 22.5277 -25.3307
71 O1a O 23.7871 -26.0303
72 C1b C 29.8738 -25.3307
73 C1c C 31.1331 -26.0303
74 C1a C 32.3225 -25.2607
75 C1a C 31.1331 -27.4296
76 C1b C 33.4419 -21.7626
77 C1c C 34.6312 -21.0630
78 C1a C 35.8905 -21.8326
79 C1a C 34.6312 -19.6637
80 C1b C 44.7058 -23.1619
81 C1a C 45.8951 -23.8615
82 C1b C 38.2693 -25.9603
83 C1b C 38.2693 -27.4296
84 N1b N 37.0099 -28.1292
85 C2c C 35.8206 -27.4296
86 N1a N 34.6312 -28.1292
87 N2a N 35.8206 -25.9603
BOND 92
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 3 6 2
6 4 7 1
7 4 8 2
8 5 9 1
9 7 10 1
10 9 11 1
11 10 12 1
12 11 13 1
13 11 14 2
14 12 15 1
15 12 16 2
16 13 17 1
17 15 18 1
18 15 19 1
19 17 20 1
20 17 21 1
21 18 22 1
22 19 23 1
23 20 24 1
24 21 25 1
25 21 26 2
26 23 27 2
27 24 28 2
28 24 29 1
29 25 30 1
30 28 31 1
31 29 32 2
32 30 33 1
33 31 34 2
34 33 35 1
35 33 36 2
36 34 37 1
37 35 38 1
38 38 39 1
39 39 40 1
40 39 41 2
41 40 42 1
42 42 43 1
43 42 44 1
44 43 45 1
45 43 46 2
46 45 47 1
47 45 48 1
48 47 49 1
49 47 50 1
50 48 51 1
51 50 52 1
52 50 53 2
53 22 23 1
54 32 34 1
55 49 51 1
56 1 54 1
57 54 55 1
58 55 56 1
59 56 58 2
60 56 59 1
61 57 60 1
62 58 61 1
63 59 62 2
64 61 63 2
65 58 60 1
66 62 63 1
67 57 55 2
68 7 64 1
69 64 65 1
70 65 66 2
71 66 67 1
72 67 68 2
73 68 69 1
74 69 65 1
75 9 70 1
76 70 71 1
77 30 72 1
78 72 73 1
79 73 74 1
80 73 75 1
81 38 76 1
82 76 77 1
83 77 78 1
84 77 79 1
85 52 80 1
86 80 81 1
87 44 82 1
88 82 83 1
89 83 84 1
90 84 85 1
91 85 86 1
92 85 87 2
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