| Entry |
|
|---|
| Name |
Loracarbef (INN);
Lorbef (TN) |
|---|
| Formula |
C16H16ClN3O4
|
|---|
| Exact mass |
349.0829
|
|---|
| Mol weight |
349.7689
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01711 Carbacephem
DG01775 Second-generation cephalosporin
|
|---|
| Remark |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DC Second-generation cephalosporins
J01DC08 Loracarbef
D08143 Loracarbef (INN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01711 Carbacephem
DG00564 Loracarbef
D08143 Loracarbef
DG01775 Second-generation cephalosporin
DG00564 Loracarbef
D08143 Loracarbef
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
D08143 Loracarbef (INN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01711 Carbacephem
DG00564 Loracarbef
DG01775 Second-generation cephalosporin
DG00564 Loracarbef
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
DG00564 Loracarbef
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 24
1 N1y N 21.1622 -16.6058
2 C1y C 21.1622 -15.1346
3 C5x C 19.7610 -16.6058
4 C2y C 22.3533 -17.3064
5 C1y C 19.7610 -15.1346
6 C1x C 22.3533 -14.5040
7 O5x O 18.7101 -17.5867
8 C2y C 23.5443 -16.6058
9 C6a C 22.3533 -18.7076
10 N1b N 18.4999 -14.5040
11 C1x C 23.5443 -15.1346
12 X Cl 24.8054 -17.3064
13 O6a O 21.1622 -19.3382
14 O6a O 23.5443 -19.3382
15 C5a C 17.3089 -15.2046
16 C1c C 16.1179 -14.5040
17 O5a O 17.3089 -16.6058
18 C8y C 14.8568 -15.2046
19 N1a N 16.1179 -13.1028
20 C8x C 14.8568 -16.6058
21 C8x C 13.6658 -14.5040
22 C8x C 13.6658 -17.3064
23 C8x C 12.4747 -15.2046
24 C8x C 12.4747 -16.6058
BOND 26
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 4 9 1
9 5 10 1 #Up
10 6 11 1
11 8 12 1
12 9 13 1
13 9 14 2
14 10 15 1
15 15 16 1
16 15 17 2
17 16 18 1
18 16 19 1 #Up
19 18 20 1
20 18 21 2
21 20 22 2
22 21 23 1
23 22 24 1
24 3 5 1
25 8 11 1
26 23 24 2
|
|---|
