| Entry |
|
|---|
| Name |
Medroxyprogesterone (INN);
Farlutal inyectable (TN) |
|---|
| Formula |
C22H32O3
|
|---|
| Exact mass |
344.2351
|
|---|
| Mol weight |
344.4877
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG02004 Progesterone
DG01666 Progesterone receptor agonist
|
|---|
| Remark |
| Product (DG00458): | D00951<JP/US> |
|
|---|
| Efficacy |
Antineoplastic, Contraceptive, Progesterone receptor agonist |
|---|
| Comment |
Progestin
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
G03AC Progestogens
G03AC06 Medroxyprogesterone
D08166 Medroxyprogesterone (INN)
G03D PROGESTOGENS
G03DA Pregnen (4) derivatives
G03DA02 Medroxyprogesterone
D08166 Medroxyprogesterone (INN)
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L02 ENDOCRINE THERAPY
L02A HORMONES AND RELATED AGENTS
L02AB Progestogens
L02AB02 Medroxyprogesterone
D08166 Medroxyprogesterone (INN)
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00458 Medroxyprogesterone
D08166 Medroxyprogesterone
DG01666 Progesterone receptor agonist
DG00458 Medroxyprogesterone
D08166 Medroxyprogesterone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D08166 Medroxyprogesterone (INN)
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00458 Medroxyprogesterone
DG01666 Progesterone receptor agonist
DG00458 Medroxyprogesterone
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 25
1 C1z C 27.6500 -15.9600
2 C1z C 26.5300 -16.5900
3 C1x C 28.8400 -16.6600
4 O1a O 28.8400 -15.2600
5 C5a C 27.7200 -14.5600
6 C1y C 26.5300 -17.9900
7 C1x C 25.3400 -15.9600
8 C1a C 26.5300 -15.2600
9 C1x C 28.8400 -17.9900
10 C1a C 26.4600 -13.8600
11 O5a O 28.9100 -13.8600
12 C1y C 25.3400 -18.6900
13 C1x C 24.1500 -16.5900
14 C1y C 24.1500 -17.9900
15 C1x C 25.3400 -20.0200
16 C1z C 22.9600 -18.6200
17 C1y C 24.1500 -20.7200
18 C2y C 22.9600 -20.0200
19 C1x C 21.7700 -17.9200
20 C1a C 22.9600 -17.2900
21 C1a C 24.1500 -22.0500
22 C2x C 21.7700 -20.7200
23 C1x C 20.5800 -18.6200
24 C5x C 20.5800 -20.0200
25 O5x O 19.3900 -20.7200
BOND 28
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 1 5 1 #Up
5 2 6 1
6 2 7 1
7 2 8 1 #Up
8 3 9 1
9 5 10 1
10 5 11 2
11 6 12 1
12 7 13 1
13 12 14 1
14 12 15 1
15 14 16 1
16 15 17 1
17 16 18 1
18 16 19 1
19 16 20 1 #Up
20 17 21 1 #Down
21 18 22 2
22 19 23 1
23 22 24 1
24 24 25 2
25 6 9 1
26 13 14 1
27 17 18 1
28 23 24 1
|
|---|
