| Entry |
|
|---|
| Name |
Megestrol (INN);
Chronopil (TN) |
|---|
| Formula |
C22H30O3
|
|---|
| Exact mass |
342.2195
|
|---|
| Mol weight |
342.4718
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG02004 Progesterone
DG01666 Progesterone receptor agonist
|
|---|
| Remark |
| Product (DG00457): | D00952<US> |
|
|---|
| Efficacy |
Antineoplastic, Contraceptive, Progesterone receptor agonist |
|---|
| Comment |
Progestin
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
G03AC Progestogens
G03AC05 Megestrol
D08167 Megestrol (INN)
G03D PROGESTOGENS
G03DB Pregnadien derivatives
G03DB02 Megestrol
D08167 Megestrol (INN)
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L02 ENDOCRINE THERAPY
L02A HORMONES AND RELATED AGENTS
L02AB Progestogens
L02AB01 Megestrol
D08167 Megestrol (INN)
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00457 Megestrol
D08167 Megestrol
DG01666 Progesterone receptor agonist
DG00457 Megestrol
D08167 Megestrol
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D08167 Megestrol (INN)
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00457 Megestrol
DG01666 Progesterone receptor agonist
DG00457 Megestrol
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 25
1 C1y C 25.3400 -18.7600
2 C1y C 26.5300 -18.0600
3 C1y C 24.1500 -18.0600
4 C2x C 25.3400 -20.1600
5 C1z C 26.5300 -16.7300
6 C1x C 28.9100 -18.1300
7 C1z C 22.9600 -18.7600
8 C1x C 24.1500 -16.6600
9 C2y C 24.1500 -20.7900
10 C1z C 27.7200 -16.0300
11 C1x C 25.3400 -16.0300
12 C1a C 26.6000 -15.4700
13 C1x C 28.9100 -16.7300
14 C2y C 22.9600 -20.0900
15 C1x C 21.7700 -18.0600
16 C1a C 23.0300 -17.5000
17 C1a C 24.1500 -22.1900
18 C5a C 27.7200 -14.6300
19 O1a O 28.9800 -15.1900
20 C2x C 21.7700 -20.7900
21 C1x C 20.5800 -18.7600
22 C1a C 26.6000 -13.9300
23 O5a O 28.8400 -13.7200
24 C5x C 20.5800 -20.0900
25 O5x O 19.3900 -20.7900
BOND 28
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 2
9 5 10 1
10 5 11 1
11 5 12 1 #Up
12 6 13 1
13 7 14 1
14 7 15 1
15 7 16 1 #Up
16 9 17 1
17 10 18 1 #Up
18 10 19 1 #Down
19 14 20 2
20 15 21 1
21 18 22 1
22 18 23 2
23 20 24 1
24 24 25 2
25 8 11 1
26 9 14 1
27 10 13 1
28 21 24 1
|
|---|
