| Entry |
|
|---|
| Name |
Mepyramine (INN) |
|---|
| Formula |
C17H23N3O
|
|---|
| Exact mass |
285.1841
|
|---|
| Mol weight |
285.384
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Comment |
Phenbenzamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA02 Mepyramine
D08183 Mepyramine (INN)
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AC Substituted ethylene diamines
R06AC01 Mepyramine
D08183 Mepyramine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00382 Mepyramine
D08183 Mepyramine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D08183 Mepyramine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00382 Mepyramine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C8x C 20.5100 -16.8700
2 C8y C 20.5100 -18.2700
3 C8x C 21.7700 -18.9700
4 C8x C 22.9600 -18.2700
5 C8y C 22.9600 -16.8700
6 C8x C 21.7700 -16.1700
7 O2a O 19.3200 -18.9700
8 C1a C 18.1300 -18.2700
9 C1b C 24.2200 -16.1700
10 N1c N 25.4100 -16.8700
11 C1b C 26.6000 -16.1700
12 C1b C 27.7900 -16.8700
13 C8y C 25.4100 -18.2700
14 N5x N 24.1500 -19.0400
15 C8x C 24.1500 -20.4400
16 C8x C 25.4100 -21.1400
17 C8x C 26.6000 -20.3700
18 C8x C 26.6000 -18.9700
19 N1c N 28.9800 -16.1700
20 C1a C 30.1700 -16.8700
21 C1a C 28.9800 -14.7700
BOND 22
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 7 8 1
9 5 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 10 13 1
14 13 14 2
15 14 15 1
16 15 16 2
17 16 17 1
18 17 18 2
19 13 18 1
20 12 19 1
21 19 20 1
22 19 21 1
|
|---|
