| Entry |
|
|---|
| Name |
Metamfetamine (INN);
Methamphetamine |
|---|
| Formula |
C10H15N
|
|---|
| Exact mass |
149.1204
|
|---|
| Mol weight |
149.2328
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01971 Agents for narcolepsy
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
|
|---|
| Remark |
| Product (DG00968): | D02242<JP/US> |
|
|---|
| Efficacy |
Psychostimulant, Stimulant (central) |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07234 | Neurotransmitter transporter inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
N06BA Centrally acting sympathomimetics
N06BA03 Metamfetamine
D08187 Metamfetamine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01971 Agents for narcolepsy
DG00968 Metamfetamine
D08187 Metamfetamine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00968 Metamfetamine
D08187 Metamfetamine
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D08187 Metamfetamine (INN)
SLC6A3 (DAT1)
D08187 Metamfetamine (INN)
SLC6A4 (HTT)
D08187 Metamfetamine (INN)
SLC18
SLC18A1 (VMAT1)
D08187 Metamfetamine (INN)
SLC18A2 (VMAT2)
D08187 Metamfetamine (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08187
Narcotics and psychotropics in Japan [br08308.html]
Stimulants by Control Act Article 2 Appended Table and Cabinet Order
D08187
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01971 Agents for narcolepsy
DG00968 Metamfetamine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00968 Metamfetamine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 11
1 C8y C 17.4300 -15.4700
2 C1b C 18.6200 -14.7700
3 C8x C 16.1700 -14.7700
4 C8x C 17.4300 -16.8700
5 C1c C 19.8100 -15.4700
6 C8x C 14.9800 -15.4700
7 C8x C 16.1700 -17.5700
8 N1b N 21.0000 -14.7700
9 C1a C 19.8100 -16.8700
10 C8x C 14.9800 -16.8700
11 C1a C 22.2600 -15.4700
BOND 11
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 2
7 5 8 1
8 5 9 1 #Up
9 6 10 2
10 8 11 1
11 7 10 1
|
|---|
