| Entry |
|
|---|
| Name |
Mosapramine (INN) |
|---|
| Formula |
C28H35ClN4O
|
|---|
| Exact mass |
478.2499
|
|---|
| Mol weight |
479.0567
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01942 Iminobenzyl antipsychotic
|
|---|
| Remark |
| Product (DG00905): | D01548<JP> |
|
|---|
| Efficacy |
Antipsychotic |
|---|
| Comment |
Iminodibenzyl derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07213 | Dopamine receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AX Other antipsychotics
N05AX10 Mosapramine
D08235 Mosapramine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00905 Mosapramine
D08235 Mosapramine
DG03200 Antipsychotic agent
DG01942 Iminobenzyl antipsychotic
DG00905 Mosapramine
D08235 Mosapramine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D08235 Mosapramine (INN)
Serotonin
HTR2A
D08235 Mosapramine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00905 Mosapramine
DG03200 Antipsychotic agent
DG01942 Iminobenzyl antipsychotic
DG00905 Mosapramine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 34
1 C1x C 19.2615 -19.4021
2 C8y C 18.4911 -18.2815
3 C8y C 18.7713 -16.9508
4 N1y N 20.0320 -16.3905
5 C1x C 20.6623 -19.4021
6 C8y C 21.2926 -17.0209
7 C8y C 21.5728 -18.3516
8 C8x C 17.7907 -15.9703
9 C8y C 16.4600 -16.3905
10 C8x C 16.1098 -17.7212
11 C8x C 17.1604 -18.7018
12 C8x C 22.9035 -18.7718
13 C8x C 23.9541 -17.8613
14 C8x C 23.6739 -16.4605
15 C8x C 22.3432 -16.0403
16 C1b C 20.0320 -14.9897
17 C1b C 21.2226 -14.3594
18 C1b C 22.4132 -15.0598
19 N1y N 23.6739 -14.4294
20 C1x C 24.8646 -15.1298
21 C1x C 26.1253 -14.4995
22 C1z C 26.1253 -13.0987
23 C1x C 24.9346 -12.3283
24 C1x C 23.6739 -13.0287
25 N1y N 27.1758 -14.0092
26 C1y C 28.4365 -13.3088
27 N1x N 28.0863 -11.9081
28 C5x C 26.6856 -11.7680
29 C1x C 27.1758 -15.4100
30 C1x C 28.3665 -16.1104
31 C1x C 29.6272 -15.4100
32 C1x C 29.6272 -14.0092
33 O5x O 25.9852 -10.5773
34 X Cl 15.4358 -15.4149
BOND 39
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 19 24 1
28 22 25 1
29 25 26 1
30 26 27 1
31 27 28 1
32 22 28 1
33 25 29 1
34 29 30 1
35 30 31 1
36 31 32 1
37 26 32 1
38 28 33 2
39 9 34 1
|
|---|
