| Entry |
|
|---|
| Name |
Oxyphenbutazone (INN);
Reozon (TN);
Oxyphenbutazone (TN) |
|---|
| Formula |
C19H20N2O3
|
|---|
| Exact mass |
324.1474
|
|---|
| Mol weight |
324.3737
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01947 Anti-inflammatory drug, pyrazolone
DG01949 Anti-inflammatory drug, phenylbutazones
|
|---|
| Remark |
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory, Antipyretic, Antirheumatic, COX inhibitor |
|---|
| Comment |
Nonsteroidal anti-inflammatory drug (NSAID)
Pyrazolone derivative phenylbutazone type
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AA Butylpyrazolidines
M01AA03 Oxyphenbutazone
D08324 Oxyphenbutazone (INN)
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA04 Oxyphenbutazone
D08324 Oxyphenbutazone (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BC Antiinflammatory agents, non-steroids
S01BC02 Oxyphenbutazone
D08324 Oxyphenbutazone (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01947 Anti-inflammatory drug, pyrazolone
DG01949 Anti-inflammatory drug, phenylbutazones
DG00746 Oxyphenbutazone
D08324 Oxyphenbutazone
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D08324 Oxyphenbutazone (INN)
PTGS2 (COX2)
D08324 Oxyphenbutazone (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01947 Anti-inflammatory drug, pyrazolone
DG01949 Anti-inflammatory drug, phenylbutazones
DG00746 Oxyphenbutazone
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 24
1 C1y C 25.6200 -17.9200
2 C1b C 27.0200 -17.9200
3 C5x C 24.7800 -16.8000
4 N1y N 23.4500 -17.2200
5 N1y N 23.4500 -18.6200
6 C5x C 24.7800 -19.0400
7 O5x O 25.2000 -20.3700
8 O5x O 25.2000 -15.5400
9 C8y C 19.8100 -15.1200
10 C8x C 19.8100 -16.5200
11 C8x C 21.0000 -17.2200
12 C8y C 22.2600 -16.5200
13 C8x C 22.2600 -15.1200
14 C8x C 21.0000 -14.4200
15 C8x C 19.8100 -19.3200
16 C8x C 19.8100 -20.7200
17 C8x C 21.0000 -21.4200
18 C8x C 22.2600 -20.7200
19 C8y C 22.2600 -19.3200
20 C8x C 21.0000 -18.6200
21 C1b C 27.7200 -16.7300
22 C1b C 29.1200 -16.7300
23 C1a C 29.8200 -15.5400
24 O1a O 18.5500 -14.4200
BOND 26
1 1 2 1
2 1 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 6 7 2
8 3 8 2
9 9 10 2
10 10 11 1
11 11 12 2
12 12 13 1
13 13 14 2
14 9 14 1
15 12 4 1
16 15 16 2
17 16 17 1
18 17 18 2
19 18 19 1
20 19 20 2
21 15 20 1
22 19 5 1
23 2 21 1
24 21 22 1
25 22 23 1
26 9 24 1
|
|---|
