| Entry |
|
|---|
| Name |
Pirenzepine (USAN/INN) |
|---|
| Formula |
C19H21N5O2
|
|---|
| Exact mass |
351.1695
|
|---|
| Mol weight |
351.4023
|
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| Structure |
|
|---|
| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
DG01975 Agents for peptic ulcer
|
|---|
| Remark |
| Product (DG00026): | D05276<JP> |
|
|---|
| Efficacy |
Antisecretory (gastric acid), Anti-ulcerative, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Tricyclic compound
Treatment of gastric ulcers and diabetic neuropathy
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A02 DRUGS FOR ACID RELATED DISORDERS
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
A02BX03 Pirenzepine
D08389 Pirenzepine (USAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Pirenzepine
D08389 Pirenzepine (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00026 Pirenzepine
D08389 Pirenzepine
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG00026 Pirenzepine
D08389 Pirenzepine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D08389 Pirenzepine (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00026 Pirenzepine
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG00026 Pirenzepine
|
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| Other DBs |
|
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| KCF data |
ATOM 26
1 C5x C 23.3800 -22.6800
2 C8y C 22.5400 -21.6300
3 C8y C 22.8900 -20.2300
4 N1y N 24.1500 -19.6700
5 N1x N 24.7800 -22.7500
6 C8y C 25.4100 -20.3000
7 C8y C 25.6900 -21.6300
8 C8x C 21.9100 -19.2500
9 C8x C 20.5100 -19.6700
10 C8x C 20.2300 -21.0000
11 C8x C 21.2100 -21.9800
12 C8x C 27.0200 -22.1200
13 C8x C 28.0700 -21.1400
14 C8x C 27.7900 -19.8100
15 N5x N 26.4600 -19.3200
16 O5x O 22.7500 -23.9400
17 C5a C 24.1500 -18.2700
18 C1b C 25.4100 -17.5700
19 O5a O 22.9600 -17.5700
20 N1y N 25.4100 -16.1700
21 C1x C 26.6000 -15.5400
22 C1x C 26.6000 -14.1400
23 N1y N 25.4100 -13.4400
24 C1x C 24.2200 -14.0700
25 C1x C 24.2200 -15.4700
26 C1a C 25.4100 -11.9700
BOND 29
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 1 16 2
19 4 17 1
20 17 18 1
21 17 19 2
22 18 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 24 25 1
28 20 25 1
29 23 26 1
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