| Entry |
|
|---|
| Name |
Promazine (INN);
Combelen [veterinary] (TN) |
|---|
| Formula |
C17H20N2S
|
|---|
| Exact mass |
284.1347
|
|---|
| Mol weight |
284.4191
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
|
|---|
| Remark |
|
|---|
| Efficacy |
Neuroleptic, Dopamine D2 receptor antagonist |
|---|
| Comment |
Phenothiazine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AA Phenothiazines with aliphatic side-chain
N05AA03 Promazine
D08430 Promazine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00869 Promazine
D08430 Promazine
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00869 Promazine
D08430 Promazine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D08430 Promazine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00869 Promazine
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00869 Promazine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 20
1 C8x C 19.9500 -19.0400
2 C8x C 19.9500 -20.4400
3 C8x C 21.1400 -21.1400
4 C8y C 22.4000 -20.4400
5 C8y C 22.4000 -19.0400
6 C8x C 21.1400 -18.2700
7 S2x S 23.5900 -21.1400
8 C8y C 24.7800 -20.4400
9 C8y C 24.7800 -19.0400
10 N4y N 23.5900 -18.2700
11 C8x C 26.0400 -21.1400
12 C8x C 27.2300 -20.4400
13 C8x C 27.2300 -19.0400
14 C8x C 26.0400 -18.2700
15 C1b C 23.5900 -16.8700
16 C1b C 24.7800 -16.1700
17 C1b C 25.9700 -16.8700
18 N1c N 27.1600 -16.2400
19 C1a C 28.3500 -16.8700
20 C1a C 27.1600 -14.7700
BOND 22
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 9 14 2
17 10 15 1
18 15 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 18 20 1
|
|---|
