| Entry |
|
|---|
| Name |
Protriptyline (INN) |
|---|
| Formula |
C19H21N
|
|---|
| Exact mass |
263.1674
|
|---|
| Mol weight |
263.3767
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG01728 Tricyclic antidepressant
|
|---|
| Remark |
| Product (DG00936): | D00484<US> |
|
|---|
| Efficacy |
Antidepressant |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AA Non-selective monoamine reuptake inhibitors
N06AA11 Protriptyline
D08447 Protriptyline (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00936 Protriptyline
D08447 Protriptyline
DG01728 Tricyclic antidepressant
DG00936 Protriptyline
D08447 Protriptyline
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D08447 Protriptyline (INN)
SLC6A4 (HTT)
D08447 Protriptyline (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00936 Protriptyline
DG01728 Tricyclic antidepressant
DG00936 Protriptyline
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 20
1 C2x C 22.9600 -20.5800
2 C8y C 22.1200 -19.4600
3 C8y C 22.4700 -18.0600
4 C1y C 23.7300 -17.5000
5 C2x C 24.3600 -20.5800
6 C8y C 24.9200 -18.0600
7 C8y C 25.2700 -19.5300
8 C8x C 21.4200 -17.0800
9 C8x C 20.0900 -17.5000
10 C8x C 19.7400 -18.9000
11 C8x C 20.7900 -19.8800
12 C8x C 26.6000 -19.9500
13 C8x C 27.5800 -19.0400
14 C8x C 27.3000 -17.5700
15 C8x C 25.9700 -17.1500
16 C1b C 23.7300 -16.1000
17 C1b C 24.9200 -15.4000
18 C1b C 26.1100 -16.1000
19 N1b N 27.3700 -15.3300
20 C1a C 28.5600 -16.1000
BOND 22
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
|
|---|
