| Entry |
|
|---|
| Name |
Remifentanil (INN);
Ultiva (TN) |
|---|
| Formula |
C20H28N2O5
|
|---|
| Exact mass |
376.1998
|
|---|
| Mol weight |
376.4467
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00795): | D01177<JP/US> |
|
|---|
| Efficacy |
Analgesic (narcotic), Opioid receptor agonist |
|---|
| Comment |
Phenylpiperidine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AH Opioid anesthetics
N01AH06 Remifentanil
D08473 Remifentanil (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02026 Opioid anesthetics
DG00795 Remifentanil
D08473 Remifentanil
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00795 Remifentanil
D08473 Remifentanil
Analgesic
DG01984 Opioid analgesics
DG00795 Remifentanil
D08473 Remifentanil
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D08473 Remifentanil (INN)
Narcotics and psychotropics in Japan [br08308.html]
Narcotics by Cabinet Order Article 1 (157 substances)
D08473
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02026 Opioid anesthetics
DG00795 Remifentanil
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00795 Remifentanil
Analgesic
DG01984 Opioid analgesics
DG00795 Remifentanil
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 27
1 C8x C 16.4500 -27.3700
2 C8x C 16.4500 -28.7700
3 C8x C 17.6400 -29.4700
4 C8x C 18.9000 -28.7700
5 C8y C 18.9000 -27.3700
6 C8x C 17.6400 -26.6700
7 N1c N 20.0900 -26.6700
8 C1z C 21.3500 -27.3700
9 C1x C 21.3500 -28.7700
10 C1x C 22.5400 -29.4700
11 N1y N 23.7300 -28.7700
12 C1x C 23.7300 -27.3700
13 C1x C 22.5400 -26.6700
14 C1b C 24.9900 -29.4700
15 C1b C 26.1800 -28.7700
16 C7a C 27.3700 -29.4700
17 C5a C 20.0900 -25.2700
18 O5a O 18.9000 -24.5700
19 C1b C 21.3500 -24.5700
20 C1a C 22.5400 -25.2700
21 C7a C 20.7200 -28.1400
22 O7a O 28.5881 -28.7799
23 C1a C 29.7695 -29.4750
24 O6a O 27.3586 -30.8700
25 O7a O 20.7200 -29.5400
26 O6a O 19.5666 -27.8142
27 C1a C 19.5076 -30.2400
BOND 28
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 8 13 1
15 11 14 1
16 14 15 1
17 15 16 1
18 7 17 1
19 17 18 2
20 17 19 1
21 19 20 1
22 8 21 1
23 16 22 1
24 22 23 1
25 16 24 2
26 21 25 1
27 21 26 2
28 25 27 1
|
|---|
