| Entry |
|
|---|
| Name |
Tamsulosin (INN);
Flomax (TN);
Tamsulon (TN) |
|---|
| Formula |
C20H28N2O5S
|
|---|
| Exact mass |
408.1719
|
|---|
| Mol weight |
408.5117
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
|
|---|
| Remark |
| Product (DG00490): | D01024<JP/US> |
| Product (mixture): | D11389<US> |
|
|---|
| Efficacy |
Antidysuria, alpha1-Adrenergic receptor antagonist |
|---|
| Comment |
Drug affecting the renal function and the urinary tract
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07215 | alpha-Adrenergic receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
G04CA Alpha-adrenoreceptor antagonists
G04CA02 Tamsulosin
D08560 Tamsulosin (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00490 Tamsulosin
D08560 Tamsulosin
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D08560 Tamsulosin (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00490 Tamsulosin
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 28
1 C8y C 21.6300 -15.1200
2 C1b C 20.4400 -14.4900
3 C1c C 19.2500 -15.1200
4 N1b N 18.0600 -14.4900
5 C1b C 16.8000 -15.1200
6 C1b C 15.6100 -14.4900
7 O2a O 14.4200 -15.1200
8 C8y C 13.1600 -14.4900
9 C8x C 11.9700 -15.1200
10 C8x C 21.6300 -16.5200
11 C8y C 22.8900 -17.2200
12 C8y C 24.0100 -16.5200
13 C8x C 24.0100 -15.1200
14 C8x C 22.8900 -14.4900
15 C1a C 19.2500 -16.5200
16 C8y C 13.1600 -13.0900
17 C8x C 11.9700 -12.3900
18 C8x C 10.7800 -13.0900
19 C8x C 10.7800 -14.4900
20 O2a O 14.4200 -12.3900
21 O2a O 25.2700 -17.2200
22 C1a C 26.4600 -16.5200
23 S4a S 22.8900 -18.6200
24 O3c O 24.2200 -18.6200
25 N1a N 22.8900 -20.0200
26 O3c O 21.4900 -18.6200
27 C1b C 15.6100 -13.1600
28 C1a C 16.8700 -12.4600
BOND 29
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 6 7 1
7 7 8 1
8 8 9 1
9 1 10 2
10 10 11 1
11 11 12 2
12 12 13 1
13 13 14 2
14 1 14 1
15 3 15 1 #Up
16 8 16 2
17 16 17 1
18 17 18 2
19 18 19 1
20 19 9 2
21 16 20 1
22 12 21 1
23 21 22 1
24 11 23 1
25 23 24 2
26 23 25 1
27 23 26 2
28 20 27 1
29 27 28 1
|
|---|
