| Entry |
|
|---|
| Name |
Terazosin (INN);
Terazosabb (TN) |
|---|
| Formula |
C19H25N5O4
|
|---|
| Exact mass |
387.1907
|
|---|
| Mol weight |
387.4329
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG03231 Antihypertensive
|
|---|
| Remark |
| Product (DG00491): | D00610<JP/US> D11585<US> |
|
|---|
| Efficacy |
Antidysuria, Antihypertensive, alpha1-Adrenergic receptor antagonist |
|---|
| Comment |
Prazosin derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07215 | alpha-Adrenergic receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
G04CA Alpha-adrenoreceptor antagonists
G04CA03 Terazosin
D08569 Terazosin (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00491 Terazosin
D08569 Terazosin
DG03231 Antihypertensive
DG00491 Terazosin
D08569 Terazosin
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D08569 Terazosin (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00491 Terazosin
DG03231 Antihypertensive
DG00491 Terazosin
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 28
1 C8y C 27.0900 -19.6700
2 C8y C 27.0900 -18.2700
3 C8x C 28.2800 -20.3700
4 C8y C 25.9000 -20.3700
5 N5x N 25.9000 -17.5700
6 C8x C 28.2800 -17.5700
7 C8y C 29.5400 -19.6700
8 N5x N 24.6400 -19.6700
9 N1a N 25.9000 -21.7700
10 C8y C 24.6400 -18.2700
11 C8y C 29.5400 -18.2700
12 O2a O 30.7300 -20.3700
13 N1y N 23.4500 -17.5700
14 O2a O 30.7300 -17.5700
15 C1a C 31.9200 -19.6700
16 C1x C 23.4500 -16.1700
17 C1x C 22.2600 -18.2700
18 C1a C 31.9200 -18.2700
19 C1x C 22.2600 -15.4700
20 C1x C 21.0000 -17.5700
21 N1y N 21.0000 -16.1700
22 C5a C 19.8100 -15.4700
23 C1y C 18.6200 -16.1700
24 O5a O 19.8100 -14.0700
25 C1x C 18.6200 -17.5700
26 O2x O 17.2900 -15.7500
27 C1x C 16.4500 -16.8700
28 C1x C 17.2900 -17.9900
BOND 31
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 4 9 1
9 5 10 2
10 6 11 2
11 7 12 1
12 10 13 1
13 11 14 1
14 12 15 1
15 13 16 1
16 13 17 1
17 14 18 1
18 16 19 1
19 17 20 1
20 19 21 1
21 7 11 1
22 8 10 1
23 20 21 1
24 21 22 1
25 22 23 1
26 22 24 2
27 23 25 1
28 23 26 1
29 26 27 1
30 27 28 1
31 25 28 1
|
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