| Entry |
|
|---|
| Name |
Tilidine (INN) |
|---|
| Formula |
C17H23NO2
|
|---|
| Exact mass |
273.1729
|
|---|
| Mol weight |
273.37
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
|
|---|
| Remark |
|
|---|
| Efficacy |
Analgesic, Opioid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AX Other opioids
N02AX01 Tilidine
D08597 Tilidine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00823 Tilidine
D08597 Tilidine
Analgesic
DG01984 Opioid analgesics
DG00823 Tilidine
D08597 Tilidine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D08597 Tilidine (INN)
Narcotics and psychotropics in Japan [br08308.html]
Narcotics by Cabinet Order Article 1 (157 substances)
D08597
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00823 Tilidine
Analgesic
DG01984 Opioid analgesics
DG00823 Tilidine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 20
1 C2x C 20.8600 -17.6400
2 C2x C 20.8600 -18.9700
3 C1x C 22.0500 -19.6700
4 C1x C 23.1700 -18.9700
5 C1z C 23.1700 -17.6400
6 C1y C 22.0500 -16.9400
7 C8y C 25.2000 -16.1700
8 C8x C 26.3200 -16.8700
9 C8x C 27.5100 -16.1700
10 C8x C 27.5100 -14.8400
11 C8x C 26.3200 -14.2100
12 C8x C 25.2000 -14.8400
13 N1c N 22.0500 -15.6100
14 C1a C 20.8600 -14.9100
15 C1a C 23.1700 -14.9100
16 C7a C 24.3600 -18.2700
17 O7a O 24.3600 -19.6700
18 O6a O 25.5500 -17.6400
19 C1b C 25.5500 -20.3000
20 C1a C 25.5500 -21.7000
BOND 21
1 1 2 2
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 5 7 1 #Up
8 7 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 7 12 1
14 6 13 1 #Up
15 13 14 1
16 13 15 1
17 5 16 1
18 16 17 1
19 16 18 2
20 17 19 1
21 19 20 1
|
|---|
