| Entry |
|
|---|
| Name |
Trihexyphenidyl (INN);
Apo-trihex (TN) |
|---|
| Formula |
C20H31NO
|
|---|
| Exact mass |
301.2406
|
|---|
| Mol weight |
301.4662
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG01967 Antiparkinson agent
|
|---|
| Remark |
| Product (DG00851): | D00787<JP/US> |
|
|---|
| Efficacy |
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
centrally active anticholinergic drugs
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AA Tertiary amines
N04AA01 Trihexyphenidyl
D08638 Trihexyphenidyl (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00851 Trihexyphenidyl
D08638 Trihexyphenidyl
DG01967 Antiparkinson agent
DG00851 Trihexyphenidyl
D08638 Trihexyphenidyl
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D08638 Trihexyphenidyl (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00851 Trihexyphenidyl
DG01967 Antiparkinson agent
DG00851 Trihexyphenidyl
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 22
1 C8x C 22.2262 -19.7138
2 C8x C 23.4847 -19.0147
3 C8x C 23.4846 -17.6164
4 C8x C 22.2262 -16.8473
5 C8y C 21.0376 -17.5465
6 C8x C 21.0376 -19.0147
7 C1x C 20.9676 -14.8198
8 C1y C 19.7791 -15.5190
9 C1d C 19.7792 -16.8473
10 C1x C 20.9676 -13.3516
11 C1x C 19.7092 -12.6525
12 C1x C 18.5206 -13.3516
13 C1x C 18.5206 -14.7499
14 C1b C 18.5906 -17.5465
15 C1b C 17.4021 -16.9173
16 N1y N 16.1436 -17.6164
17 C1x C 14.9550 -16.9173
18 C1x C 13.7665 -17.6164
19 C1x C 13.7665 -19.0147
20 C1x C 14.9550 -19.6439
21 C1x C 16.1436 -18.9448
22 O1a O 21.0376 -16.1482
BOND 24
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 1
8 8 9 1
9 5 9 1
10 7 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 8 13 1
15 9 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 16 21 1
24 9 22 1
|
|---|
