KEGG   DRUG: Triprolidine
Entry
D08648                      Drug                                   
Name
Triprolidine (INN)
Formula
C19H22N2
Exact mass
278.1783
Mol weight
278.3914
Structure
Simcomp
Class
Anti-allergic agent
 DG01557  Histamine receptor antagonist
  DG01482  Histamine receptor H1 antagonist
Remark
ATC code: R06AX07
Chemical structure group: DG01111
Efficacy
Antiallergic, H1 receptor antagonist
Target
HRH1 [HSA:3269] [KO:K04149]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04750  Inflammatory mediator regulation of TRP channels
Interaction
Structure map
map07212  Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AX Other antihistamines for systemic use
     R06AX07 Triprolidine
      D08648  Triprolidine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Triprolidine
    D08648  Triprolidine (INN)
Drug groups [BR:br08330]
 Anti-allergic agent
  DG01557  Histamine receptor antagonist
   DG01482  Histamine receptor H1 antagonist
    DG01111  Triprolidine
     D08648  Triprolidine
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    HRH1
     D08648  Triprolidine (INN)
Drug groups [BR:br08330]
 Anti-allergic agent
  DG01557  Histamine receptor antagonist
   DG01482  Histamine receptor H1 antagonist
    DG01111  Triprolidine
Other DBs
CAS: 486-12-4
PubChem: 96025331
ChEBI: 84116
LigandBox: D08648
NIKKAJI: J6.005D
KCF data

ATOM        21
            1   C2b C    24.7800  -17.9900
            2   C1b C    23.5200  -17.2900
            3   N1y N    23.5200  -15.8900
            4   C1x C    22.4000  -15.0500
            5   C1x C    22.8200  -13.7200
            6   C1x C    24.2200  -13.7200
            7   C1x C    24.6400  -15.0500
            8   C8x C    21.1400  -20.0900
            9   C8y C    21.1400  -21.4900
            10  C8x C    22.3300  -22.1900
            11  C8x C    23.5200  -21.4900
            12  C8y C    23.5200  -20.0900
            13  C8x C    22.3300  -19.3900
            14  C2c C    24.7800  -19.3900
            15  C8y C    25.9700  -20.0900
            16  C8x C    25.9700  -21.4900
            17  C8x C    27.1600  -22.1900
            18  C8x C    28.4200  -21.4900
            19  C8x C    28.4200  -20.0900
            20  N5x N    27.1600  -19.3900
            21  C1a C    19.8800  -22.1900
BOND        23
            1     3   4 1
            2     8   9 2
            3     9  10 1
            4    10  11 2
            5    11  12 1
            6    12  13 2
            7    13   8 1
            8     4   5 1
            9    12  14 1
            10    5   6 1
            11   14  15 1
            12    6   7 1
            13    7   3 1
            14    2   3 1
            15   15  16 2
            16   16  17 1
            17   17  18 2
            18   18  19 1
            19   19  20 2
            20   20  15 1
            21    1   2 1
            22    9  21 1
            23   14   1 2

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Drug (2)   
   KEGG DGROUP (1)   
   LigandBox (1)   
Chemical substance (11)   
   PubChem (1)   
   ChEBI (1)   
   HMDB (1)   
   HSDB (1)   
   MASSBANK (6)   
   NIKKAJI (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (20)   

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