| Entry |
|
|---|
| Name |
Yohimbine (DCF) |
|---|
| Formula |
C21H26N2O3
|
|---|
| Exact mass |
354.1943
|
|---|
| Mol weight |
354.4427
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Source |
Corynanthe johimbe [TAX: 170026]
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01460 alpha2-Adrenergic receptor antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
alpha2-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04B UROLOGICALS
G04BE Drugs used in erectile dysfunction
G04BE04 Yohimbine
D08685 Yohimbine (DCF)
Risk category of Japanese OTC drugs [BR:br08312]
First-class OTC drugs
Inorganic and organic chemicals
Yohimbine
D08685 Yohimbine (DCF)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01460 alpha2-Adrenergic receptor antagonist
DG00485 Yohimbine
D08685 Yohimbine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA2
D08685 Yohimbine (DCF)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01460 alpha2-Adrenergic receptor antagonist
DG00485 Yohimbine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 26
1 C8x C 18.4800 -15.9600
2 C8x C 18.4800 -17.2900
3 C8x C 19.7400 -17.9900
4 C8x C 19.6700 -15.1900
5 C8y C 20.8600 -15.8900
6 C8y C 20.8600 -17.2200
7 C1x C 24.0800 -13.8600
8 C1x C 22.6800 -14.0700
9 N1y N 24.9200 -14.9800
10 C1y C 24.3600 -16.2400
11 C1x C 25.2700 -17.3600
12 C1x C 26.2500 -14.7700
13 C1y C 27.1600 -15.8900
14 C1y C 26.6000 -17.1500
15 C1y C 27.4400 -18.2000
16 C1y C 28.8400 -18.0600
17 C1x C 29.3300 -16.7300
18 C1x C 28.4900 -15.6800
19 C7a C 26.8800 -19.6000
20 C8y C 23.0300 -16.4500
21 C8y C 22.1900 -15.4000
22 N4x N 22.2600 -17.6400
23 O1a O 29.8900 -19.0400
24 O7a O 27.7900 -20.7200
25 C1a C 27.2300 -22.0500
26 O6a O 25.4800 -19.9500
BOND 30
1 1 2 1
2 20 10 1
3 9 7 1
4 7 8 1
5 13 14 1
6 14 15 1
7 15 16 1
8 16 17 1
9 17 18 1
10 18 13 1
11 8 21 1
12 15 19 1 #Down
13 2 3 2
14 3 6 1
15 5 4 1
16 20 21 2
17 21 5 1
18 6 22 1
19 22 20 1
20 4 1 2
21 16 23 1 #Down
22 9 10 1
23 19 24 1
24 10 11 1
25 24 25 1
26 11 14 1
27 19 26 2
28 13 12 1
29 12 9 1
30 5 6 2
|
|---|
