| Entry |
|
|---|
| Name |
Ziprasidone (INN);
Zipradon (TN) |
|---|
| Formula |
C21H21ClN4OS
|
|---|
| Exact mass |
412.1125
|
|---|
| Mol weight |
412.9356
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
|
|---|
| Remark |
| Product (DG00892): | D01939<US> D02100<US> |
|
|---|
| Efficacy |
Antipsychotic, Neuroleptic |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AE Indole derivatives
N05AE04 Ziprasidone
D08687 Ziprasidone (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00892 Ziprasidone
D08687 Ziprasidone
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D08687 Ziprasidone (INN)
Serotonin
HTR2A
D08687 Ziprasidone (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00892 Ziprasidone
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 28
1 C8y C 14.0678 -14.6282
2 C8y C 12.8079 -15.1881
3 N1y N 15.1877 -15.3281
4 N5x N 14.0678 -13.2283
5 C8y C 11.8281 -14.1382
6 C8x C 12.3880 -16.5180
7 C1x C 15.1877 -16.7279
8 C1x C 16.4475 -14.5582
9 S2x S 12.5280 -12.9484
10 C8x C 10.4982 -14.4182
11 C8x C 10.9881 -16.7979
12 C1x C 16.5175 -17.3579
13 C1x C 17.7074 -15.2581
14 C8x C 10.0783 -15.8180
15 N1y N 17.7074 -16.6579
16 C1b C 18.8973 -17.3579
17 C1b C 20.0171 -16.6579
18 C8y C 21.2070 -17.3579
19 C8x C 22.4669 -16.6579
20 C8y C 21.2070 -18.7577
21 C8y C 23.6567 -17.3579
22 C8x C 22.4669 -19.4576
23 X Cl 20.0171 -19.4576
24 C8y C 23.6567 -18.7577
25 C1x C 24.9866 -16.9379
26 N1x N 24.9866 -19.1777
27 C5x C 25.8265 -18.0578
28 O5x O 27.2263 -18.0578
BOND 32
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 1
9 5 10 1
10 6 11 2
11 7 12 1
12 8 13 1
13 10 14 2
14 12 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 2
19 18 20 1
20 19 21 1
21 20 22 2
22 20 23 1
23 21 24 2
24 21 25 1
25 24 26 1
26 25 27 1
27 27 28 2
28 5 9 1
29 11 14 1
30 13 15 1
31 22 24 1
32 26 27 1
|
|---|
