| Entry |
|
|---|
| Name |
Duvoglustat (USAN/INN);
1-Deoxynojirimycin |
|---|
| Formula |
C6H13NO4
|
|---|
| Exact mass |
163.0845
|
|---|
| Mol weight |
163.1717
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Source |
Streptomyces subrutilis [TAX: 36818]
|
|---|
| Class |
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01663 alpha-Glucosidase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Pharmacological chaperone (alpha-glucosidase) |
|---|
| Comment |
Pharmacological chaperone
Treatment of Pompe disease
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01663 alpha-Glucosidase inhibitor
DG01280 Duvoglustat
D09605 Duvoglustat
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Glycosidases
GAA
D09605 Duvoglustat (USAN/INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01663 alpha-Glucosidase inhibitor
DG01280 Duvoglustat
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 11
1 C1y C 23.0103 -24.4835
2 C1y C 23.0103 -25.8865
3 C1y C 24.2028 -26.5880
4 C1y C 25.4656 -25.8865
5 C1x C 25.4656 -24.4835
6 N1x N 24.2028 -23.7819
7 C1b C 21.8177 -23.7819
8 O1a O 20.6251 -24.4835
9 O1a O 21.8177 -26.5880
10 O1a O 26.6582 -26.5880
11 O1a O 24.2028 -27.9911
BOND 11
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1 #Up
8 7 8 1
9 2 9 1 #Down
10 4 10 1 #Down
11 3 11 1 #Up
|
|---|
