KEGG   DRUG: Tedizolid phosphate
Entry
D09686                      Drug                                   
Name
Tedizolid phosphate (JAN/USAN);
Torezolid phosphate;
Sivextro (TN)
Product
SIVEXTRO (Merck Sharp & Dohme LLC), SIVEXTRO (Nabriva Therapeutics US)
Formula
C17H16FN6O6P
Exact mass
450.0853
Mol weight
450.3177
Structure
Simcomp
Class
Antibacterial
 DG01789  Oxazolidinone antibiotic
Remark
Therapeutic category: 6249
ATC code: J01XX11
Chemical structure group: DG01442
Product (DG01442): D09686<JP/US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
50S ribosomal subunit
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XX Other antibacterials
     J01XX11 Tedizolid
      D09686  Tedizolid phosphate (JAN/USAN) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Tedizolid
    D09686  Tedizolid phosphate (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   624  Synthetic antibacterials
    6249  Others
     D09686  Tedizolid phosphate (JAN/USAN)
Drug groups [BR:br08330]
 Antibacterial
  DG01789  Oxazolidinone antibiotic
   DG01442  Tedizolid
    D09686  Tedizolid phosphate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Oxazolidinone
    D09686  Tedizolid phosphate (JAN/USAN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D09686
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D09686
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D09686
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09686
Drug groups [BR:br08330]
 Antibacterial
  DG01789  Oxazolidinone antibiotic
   DG01442  Tedizolid
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Oxazolidinone
    DG01442  Tedizolid
Other DBs
CAS: 856867-55-5
PubChem: 124490426
ChEBI: 83326
LigandBox: D09686
KCF data

ATOM        31
            1   C8x C    17.2200  -15.8200
            2   C8y C    17.2200  -17.2200
            3   C8x C    18.4100  -17.9200
            4   C8x C    19.6700  -17.2200
            5   C8y C    19.6700  -15.8200
            6   C8y C    18.4100  -15.1200
            7   C8y C    20.8600  -15.0500
            8   C8x C    22.1200  -15.7500
            9   N5x N    23.3100  -15.0500
            10  C8y C    23.3100  -13.6500
            11  C8x C    22.1200  -12.9500
            12  C8x C    20.8600  -13.6500
            13  C8y C    24.5700  -12.9500
            14  X   F    18.4100  -13.7200
            15  N1y N    16.0300  -17.9200
            16  C1x C    14.7000  -17.5000
            17  C1y C    13.9300  -18.6200
            18  O7x O    14.7700  -19.7400
            19  C7x C    16.0300  -19.3200
            20  O6a O    17.2200  -20.0900
            21  C1b C    12.5300  -18.6900
            22  N5x N    25.9000  -13.3700
            23  N4y N    26.7400  -12.1800
            24  N5x N    25.9000  -11.0600
            25  N5x N    24.5700  -11.5500
            26  C1a C    28.1400  -12.1800
            27  O2b O    11.7600  -17.5000
            28  P1b P    10.3600  -17.5000
            29  O1c O    10.3600  -16.1000
            30  O1c O    10.3600  -18.9000
            31  O1c O     8.9600  -17.5000
BOND        34
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12   11  12 2
            13    7  12 1
            14   10  13 1
            15    6  14 1
            16    2  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   15  19 1
            22   19  20 2
            23   17  21 1 #Up
            24   13  22 2
            25   22  23 1
            26   23  24 1
            27   24  25 2
            28   13  25 1
            29   23  26 1
            30   21  27 1
            31   27  28 1
            32   28  29 1
            33   28  30 2
            34   28  31 1

» Japanese version   » Back

  All links  
Ontology (9)   
   KEGG BRITE (9)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (2)   
   KEGG DGROUP (1)   
   LigandBox (1)   
Chemical substance (2)   
   PubChem (1)   
   ChEBI (1)   
All databases (14)   

Download RDF
DBGET integrated database retrieval system