Entry |
|
Name |
estradiol 17alpha-dehydrogenase;
17alpha-estradiol dehydrogenase;
17alpha-hydroxy steroid dehydrogenase;
17alpha-hydroxy steroid oxidoreductase;
17alpha-hydroxysteroid oxidoreductase;
estradiol 17alpha-oxidoreductase
|
Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
|
Sysname |
17alpha-hydroxysteroid:NAD(P)+ 17-oxidoreductase
|
Reaction(IUBMB) |
estradiol-17alpha + NAD(P)+ = estrone + NAD(P)H + H+ [RN: R02347 R02349]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
History |
EC 1.1.1.148 created 1972
|
Pathway |
ec00140 | Steroid hormone biosynthesis |
|
Reference |
|
Authors |
Renwick AG, Engel LL. |
Title |
The partial purification of 17 alpha- and 17 beta-estradiol dehydrogenase activities from chicken liver. |
Journal |
|
Other DBs |
ExPASy - ENZYME nomenclature database: | 1.1.1.148 |
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