KEGG   ENZYME: 1.1.1.15
Entry
EC 1.1.1.15                 Enzyme                                 
Name
D-iditol 2-dehydrogenase;
D-sorbitol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-iditol:NAD+ 2-oxidoreductase
Reaction(IUBMB)
D-iditol + NAD+ = D-sorbose + NADH + H+ [RN:R02896]
Reaction(KEGG)
R02896;
(other) R00875 R05831 R08536
Substrate
D-iditol [CPD:C01489];
NAD+ [CPD:C00003]
Product
D-sorbose [CPD:C00764];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also converts xylitol into L-xylulose and L-glucitol into L-fructose.
History
EC 1.1.1.15 created 1961
Pathway
ec00040  Pentose and glucuronate interconversions
ec00051  Fructose and mannose metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:13373783]
  Authors
SHAW DR.
  Title
Polyol dehydrogenases.  3.  Galactitol dehydrogenase and D-iditol dehydrogenase.
  Journal
Biochem J 64:394-405 (1956)
DOI:10.1042/bj0640394
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.15
IUBMB Enzyme Nomenclature: 1.1.1.15
ExPASy - ENZYME nomenclature database: 1.1.1.15
BRENDA, the Enzyme Database: 1.1.1.15
CAS: 9028-22-2

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