KEGG   ENZYME: 1.1.1.150
Entry
EC 1.1.1.150                Enzyme                                 
Name
21-hydroxysteroid dehydrogenase (NAD+);
21-hydroxysteroid dehydrogenase (NAD+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
21-hydroxysteroid:NAD+ 21-oxidoreductase
Reaction(IUBMB)
pregnan-21-ol + NAD+ = pregnan-21-al + NADH + H+ [RN:R03043]
Reaction(KEGG)
R03043
Substrate
pregnan-21-ol [CPD:C00892];
NAD+ [CPD:C00003]
Product
pregnan-21-al [CPD:C00891];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Acts on a number of 21-hydroxycorticosteroids.
History
EC 1.1.1.150 created 1972
Reference
1  [PMID:14253469]
  Authors
MONDER C, WHITE A.
  Title
THE 21-HYDROXYSTEROID DEHYDROGENASES OF LIVER. A NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE AND TWO NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASES.
  Journal
J Biol Chem 240:71-7 (1965)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.150
IUBMB Enzyme Nomenclature: 1.1.1.150
ExPASy - ENZYME nomenclature database: 1.1.1.150
BRENDA, the Enzyme Database: 1.1.1.150
CAS: 37250-75-2

  All links  
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
All databases (7)   

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