| Entry |
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| Name |
glucuronate reductase;
L-hexonate:NADP dehydrogenase;
TPN-L-gulonate dehydrogenase;
NADP-L-gulonate dehydrogenase;
D-glucuronate dehydrogenase;
D-glucuronate reductase;
L-glucuronate reductase (incorrect)
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
L-gulonate:NADP+ 6-oxidoreductase
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| Reaction(IUBMB) |
L-gulonate + NADP+ = D-glucuronate + NADPH + H+ [RN: R01481]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Also reduces D-galacturonate. May be identical with EC 1.1.1.2 [alcohol dehydrogenase (NADP+)].
|
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| History |
EC 1.1.1.19 created 1961
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| Pathway |
| ec00040 | Pentose and glucuronate interconversions |
| ec00053 | Ascorbate and aldarate metabolism |
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| Reference |
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| Authors |
SIVAK A, HOFFMANN-OSTENHOF O. |
|---|
| Title |
Enzymes of mesoinositol catabolism in the yeast Schwanniomyces accidentalis. |
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| Journal |
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| Reference |
2 |
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| Authors |
von Wartburg, J.P. and Wermoth, B. |
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| Title |
Aldehyde reductase. |
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| Journal |
In: Jakoby, W.B. (Ed.), Enzymatic Basis of Detoxication, vol. 1, Academic Press, New York, 1980, p. 249-260. |
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| Reference |
|
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| Authors |
YORK JL, GROLLMAN AP, BUBLITZ C. |
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| Title |
TPN-L-gluonate dehydrogenase. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.1.1.19 |
| ExPASy - ENZYME nomenclature database: | 1.1.1.19 |
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