KEGG   ENZYME: 1.1.1.254
Entry
EC 1.1.1.254                Enzyme                                 
Name
(S)-carnitine 3-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(S)-carnitine:NAD+ oxidoreductase
Reaction(IUBMB)
(S)-carnitine + NAD+ = 3-dehydrocarnitine + NADH + H+ [RN:R01921]
Reaction(KEGG)
R01921
Substrate
(S)-carnitine [CPD:C15025];
NAD+ [CPD:C00003]
Product
3-dehydrocarnitine [CPD:C02636];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Specific for the (S)-enantiomer of carnitine, i.e., the enantiomer of the substrate of EC 1.1.1.108 carnitine 3-dehydrogenase
History
EC 1.1.1.254 created 1999
Reference
1  [PMID:9214773]
  Authors
Setyahadi S, Ueyama T, Arimoto T, Mori N, Kitamoto Y.
  Title
Purification and properties of a new enzyme, D-carnitine dehydrogenase, from Agrobacterium sp. 525a.
  Journal
Biosci Biotechnol Biochem 61:1055-8 (1997)
DOI:10.1271/bbb.61.1055
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.254
IUBMB Enzyme Nomenclature: 1.1.1.254
ExPASy - ENZYME nomenclature database: 1.1.1.254
BRENDA, the Enzyme Database: 1.1.1.254
CAS: 154215-16-4 169277-49-0

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