KEGG ENZYME: 1.1.1.288

ENZYME: 1.1.1.288

Entry

EC 1.1.1.288                Enzyme

Name

xanthoxin dehydrogenase;
xanthoxin oxidase;
ABA2

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

xanthoxin:NAD+ oxidoreductase

Reaction(IUBMB)

xanthoxin + NAD+ = abscisic aldehyde + NADH + H+ [RN:R06954]

Reaction(KEGG)

R06954

Substrate

xanthoxin [CPD:C13453];
NAD+ [CPD:C00003]

Product

abscisic aldehyde [CPD:C13455];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

Requires a molybdenum cofactor for activity. NADP+ cannot replace NAD+ and short-chain alcohols such as ethanol, isopropanol, butanol and cyclohexanol cannot replace xanthoxin as substrate [3]. Involved in the abscisic-acid biosynthesis pathway in plants, along with EC 1.2.3.14 (abscisic-aldehyde oxidase), EC 1.13.11.51 (9-cis-epoxycarotenoid dioxygenase) and EC 1.14.13.93 [(+)-abscisic acid 8'-hydroxylase]. Abscisic acid is a sesquiterpenoid plant hormone that is involved in the control of a wide range of essential physiological processes, including seed development, germination and responses to stress [3].

History

EC 1.1.1.288 created 2005

Pathway

ec00906

Carotenoid biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K09841

xanthoxin dehydrogenase

Genes

ATH:	AT1G52340(ABA2)

ALY:

9327753

CRB:

17896886

CSAT:

104758555 104778156

EUS:	EUTSA_v10011636mg

BRP:	103832798 103871215

BNA:	106345736 106390565

BOE:

106300040

RSZ:

108860834

THJ:

104821959

CPAP:

110815871

CIT:	102577974(ABA2)

CIC:	CICLE_v10012415mg

PVY:

116143607

MINC:

123215053

TCC:

18585758

GRA:

105783205

GHI:	107920536 107933310

GAB:

108461096

HSYR:

120162557

DZI:	111295129 111310084

EGR:

104454559

GMX:	100786658 100801691

GSJ:	114374582 114376976

PVU:	PHAVU_005G031500g PHAVU_005G031600g

VRA:	106760860 106761417

VAR:	108333217 108333278

VUN:	114162538 114176348

VUM:	124842493 124845387

CCAJ:

109809099 109815886

APRC:

113867779

MTR:

11414690

CAM:

101515018

PSAT:

127085747

VVO:

131631924

LJA:	Lj0g3v0091119.1(Lj0g3v0091119.1)

ADU:

107471843

AIP:

107622404

AHF:	112717010 112782563

LANG:

109335868

PCIN:

129295431 129296353

QSA:	O6P43_029656

FVE:

101292810

RCN:

112179057

PPER:

18785370

PMUM:

103343399

PAVI:

110747964 110770832

PDUL:

117620278

MDM:	103431475 103446486 114819149

MSYL:

126600708 126628499 126628501

PXB:	103945571 103957656 103957657

ZJU:

125422308

MNT:

21391964

CSAV:

115698597

CSV:

101219413

CMO:

103503321

BHJ:

120092550

MCHA:

111024504

CMAX:

111489670

CMOS:

111445228

CPEP:

111808179

RCU:	8270915 8280319

JCU:

105631198

HBR:

110661036

MESC:

110613693

POP:

7487015

PEU:

105107390

PALZ:

118061218

JRE:	108988748 108988790 108988885 108989891

CILL:

122289539 122294916

CAVE:

132185686

QSU:	112022992 112022997 112023002

QLO:	115986376 115986377 115986378

TWL:	119988731 119989639 119989664 119989851 120006222 120006223

VVI:

100265470

VRI:

117927554

SLY:	101254297 101254591

SPEN:

107015744 107018349 107019321

SOT:	102577811 102584670

SSTN:

125856475 125856853

SDUL:

129902627 129904323

CANN:

107855067 107855068

LBB:	132627371 132627373

NTA:	107760487 107765743 107765752 107778136

NSY:	104235616 104237462

NTO:	104121195 104121196

NAU:	109207455 109209388

INI:

109155970

ITR:

115997558

SIND:

105172159

OEU:

111410241

EGT:	105951798 105957017

SSPL:

121756256 121759247

SMIL:

130994657 131022895

SHIS:

125223514 125223696

APAN:

127261320 127262583

HAN:

110925709

ECAD:

122603241 122605147

LSV:	111876124 111916298

CCAV:

112515797

DCR:

108206649

CSIN:

114297049

RVL:

131334732

AEW:

130783853

BVG:	104888541 104888542 104888543

SOE:	110784079 110784166

CQI:	110697046 110729644

ATRI:

130805838 130805839

MOF:

131163849

NNU:

104612004

MING:

122090896

TSS:	122648330 122672765 122672766

PSOM:

113312628

OSA:

4334535

DOSA:

Os03t0810800-01(Os03g0810800)

OBR:

102708142

OGL:

127766755

BDI:

100827045

ATS:

109784728

TDC:	119303737 119312419 119350087

TAES:

123105588 123113898 123123404

TUA:

125511092

LPER:

127292200

LRD:

124701005

SBI:

8057083

ZMA:

100282128

SITA:

101756331 101757665

SVS:	117836315 117838061

PVIR:

120649344 120687980

PHAI:

112874733 112874734

PDA:	103720715 103720728

EGU:	105045553 105045554 105052461

MUS:

103981080

ZOF:	122041394 122045892

DCT:

110111993

PEQ:

110031715

AOF:

109848475

MSIN:

131250792

NCOL:

116257606 116257618

ATR:

18433242

» show all

Reference

1 [PMID:16666262]

Authors

Sindhu RK, Walton DC.

Title

Xanthoxin Metabolism in Cell-free Preparations from Wild Type and Wilty Mutants of Tomato.

Journal

Plant Physiol 88:178-182 (1988)
DOI:10.1104/pp.88.1.178

Reference

2 [PMID:9159947]

Authors

Schwartz SH, Leon-Kloosterziel KM, Koornneef M, Zeevaart JA.

Title

Biochemical characterization of the aba2 and aba3 mutants in Arabidopsis thaliana.

Journal

Plant Physiol 114:161-6 (1997)
DOI:10.1104/pp.114.1.161

Sequence

[ath:AT1G52340]

Reference

3 [PMID:12172025]

Authors

Gonzalez-Guzman M, Apostolova N, Belles JM, Barrero JM, Piqueras P, Ponce MR, Micol JL, Serrano R, Rodriguez PL

Title

The short-chain alcohol dehydrogenase ABA2 catalyzes the conversion of xanthoxin to abscisic aldehyde.

Journal

Plant Cell 14:1833-46 (2002)
DOI:10.1105/tpc.002477

Sequence

[ath:AT1G52340]

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.288

IUBMB Enzyme Nomenclature:

1.1.1.288

ExPASy - ENZYME nomenclature database:

1.1.1.288

BRENDA, the Enzyme Database:

1.1.1.288

CAS:	129204-37-1

DBGET integrated database retrieval system