KEGG   ENZYME: 1.1.1.335
Entry
EC 1.1.1.335                Enzyme                                 
Name
UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase;
WlbA;
WbpB
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronate:NAD+ 3-oxidoreductase
Reaction(IUBMB)
UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronate + NAD+ = UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + NADH + H+ [RN:R10140]
Reaction(KEGG)
R10140
Substrate
UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronate [CPD:C04573];
NAD+ [CPD:C00003]
Product
UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate [CPD:C20395];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
This enzyme participates in the biosynthetic pathway for UDP-alpha-D-ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid), an important precursor of B-band lipopolysaccharide. The enzymes from Pseudomonas aeruginosa serotype O5 and Thermus thermophilus form a complex with the the enzyme catalysing the next step the pathway (EC 2.6.1.98, UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase). The enzyme also possesses an EC 1.1.99.2 (L-2-hydroxyglutarate dehydrogenase) activity, and utilizes the 2-oxoglutarate produced by EC 2.6.1.98 to regenerate the tightly bound NAD+. The enzymes from Bordetella pertussis and Chromobacterium violaceum do not bind NAD+ as tightly and do not require 2-oxoglutarate to function.
History
EC 1.1.1.335 created 2012
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K13016  UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
K13020  UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
Genes
CBRA: A6J81_14380
CWE: CO701_19350
CAMA: F384_24285
CFAR: CI104_22315
CTEL: GBC03_07515
BUF: D8682_19095
BAGE: BADSM9389_06600
BFT: MNO13_03405
EBB: F652_2264
SMAF: D781_0082
RAH: Rahaq_1175
RACE: JHW33_00230
RAQ: Rahaq2_1252
RAA: Q7S_05670
ROX: BV494_01215
RVC: J9880_13720
RBON: QNM34_06020
RIU: I2123_07930
SOD: Sant_2703
PAO: Pat9b_4259
PLU: plu4797(wblB)
PLUM: A4R40_23860
PAY: PAU_04312(wblB)
PTT: VY86_07520
PLUI: CE143_24590
XBO: XBJ1_4314
XNE: XNC1_0112
XNM: XNC2_0114
XGR: QL128_20445
PVC: G3341_19065
HPAR: AL518_10040
LRI: NCTC12151_03551(gfo)
MSU: MS1500(mviM)
BSUN: A4G13_04960
ASU: Asuc_0110
AAZ: ADJ80_05775
AVT: NCTC3438_01791(gfo_2)
DJI: CH75_07775
DJA: HY57_11970
DYE: EO087_12210
DCS: ISN74_19545
DTL: H8F01_18615
VTU: IX91_00690
VEU: IXK98_09355
PAE: PA3158(wbpB)
PAEV: N297_3269(wbpB)
PAEI: N296_3269(wbpB)
PAEM: U769_09132
PAEC: M802_3267(wbpB)
PAEO: M801_3134(wbpB)
PMY: Pmen_1858
PPUH: B479_06900
PAZO: AYR47_15420
PBA: PSEBR_a1558
PDR: H681_23225
PSES: PSCI_2866
PSOS: POS17_4987
PSET: THL1_1977
PXA: KSS93_10395(wbpB)
PANH: HU763_007130(wbpB)
PCAV: D3880_03190
PHF: NLY38_15670
PSIH: LOY51_07390
PHOM: KJF94_22335(wbpB)
MSR: AU15_01125
MARI: ACP86_02340
MARA: D0851_05440
MARJ: MARI_04640(wbpB)
PCR: Pcryo_0614
PRW: PsycPRwf_0247
PALI: A3K91_0139 A3K91_0719
PSYP: E5677_09790 E5677_12790
ACB: A1S_0053
ABK: LX00_00465
ABW: BL01_01445
ACC: BDGL_002972
ACD: AOLE_19130
AID: CTZ23_14935
ADS: FPL17_13950
ACHI: CDG60_01075
ASHA: G8E00_00505
AVIV: LF296_18080
SAZ: Sama_2259
SSE: Ssed_2972
SSEM: JYB85_11890
SGLA: FJ709_05395
SVM: KDH10_000086
SRHS: K0I63_07035
IPI: CEW91_09915
IDI: CWC33_02945
PSEO: OM33_04950
PLZ: S4054249_18600
PPIS: B1L02_14600
PXI: J5O05_07160
PVB: J5X90_03255 J5X90_03345
PSAZ: PA25_03820(wbpB)
PFLI: CTT31_02695
PMAZ: R5H13_02710
AAL: EP13_13975
AAUS: EP12_05245
ASP: AOR13_496
ASQ: AVL57_16025
AAW: AVL56_14960
ALE: AV939_14935
ALZ: AV940_14685
LAL: AT746_12775
CATE: C2869_02600 C2869_15620
PAEW: KIH87_04760
ALKM: NKI27_13880
PMAW: MACH26_32840
CELL: CBR65_17455
SDE: Sde_0872
AFUS: EYZ66_11590
LFA: LFA_0788
LOK: Loa_02107
LWA: SAMEA4504053_1071(gfo)
LSS: NCTC12082_00067(gfo)
MBUR: EQU24_04405
FRX: F7310_06790
FRL: FIP56_02755
CYY: CPC19_11160
TLH: NR989_02445
TANI: J8380_09335
TMB: Thimo_0036
THIM: KFB96_04800
TLR: Thiosp_00142(wbpB_1) Thiosp_04203(wbpB_2)
TNI: TVNIR_0687(pht4_[H])
TTI: THITH_05750
SPIZ: GJ672_09095
SEDS: AAY24_11380
HAHE: ENC22_10775
HAHH: O5O45_01625
HCO: LOKO_02148(wbpB)
HALO: BWR19_11915
HSV: HNO53_09795
HPIZ: GYM47_15080
HTT: HZS52_20505
HCAM: I4484_08290 I4484_11335
HSX: HNO51_07700 HNO51_11040
HTX: EKK97_08735 EKK97_12330
ADI: B5T_01708(wbpB)
MMW: Mmwyl1_0822
MPRI: MP3633_3247
MFOI: JSY38_06740
MRHI: KDW99_03190
TOR: R615_06290
MGEO: CFI10_13645
OME: OLMES_5515
SUTR: L0B52_04095
ORB: IPMB12_01885
SDF: ACG33_04725
THIN: CRN91_03260
NEL: NELON_10585
NSI: A6J88_04690
NMJ: NM96_12900
NEI: BG910_03000
NEK: CGZ77_00960
NZL: D0T92_00375
NZO: SAMEA4504057_0083(iolG)
NANI: NCTC12227_01671(gfo)
NBC: H3L91_10800
NMUS: H7A79_1726
NSC: J7445_11470
NDN: H3L92_00305
NDU: LVJ88_11205
NMB: MON40_05915
VFF: VITFI_CDS0485
VIT: ADP71_03400
VST: LVJ81_10700
VMS: LVJ82_06285
NBA: CUN60_03460 CUN60_12660
PTES: JQU52_03225
MCER: MON37_00925
CCAH: DWG20_03065
CVI: CV_4127
CVC: BKX93_16815
CHRO: CXB49_18575
CHRI: DK842_10875
CHRB: DK843_16310
CRZ: D1345_02465
CHRM: FYK34_19605
CHAE: CH06BL_04730(wlbA) CH06BL_39690(wlbA)
PSE: NH8B_0413
AMAH: DLM_4446
AQS: DKK66_05305
VOG: LCH97_14395
CARI: FNU76_04840
CKS: H9L41_03400
LHK: LHK_02805(wblB)
RPJ: N234_28855
REH: H16_B0033(wbpB)
CUU: BKK79_06660
COX: E0W60_06205
PPNO: DA70_17270
LMIR: NCTC12852_00294(afr_1)
BPE: BP0093(bplA)
BPC: BPTD_0089(bplA)
BPER: BN118_0162(wlbA)
BPET: B1917_0096(bplA)
BPEU: Q425_2060(bplA)
BPAR: BN117_0153(wlbA)
BPA: BPP0155(bplA)
BBH: BN112_3256(wlbA)
BBR: BB0155(bplA)
BBM: BN115_0144(wlbA)
BBX: BBS798_0154(bplA)
BPT: Bpet4814(wlbA)
BAV: BAV0098(wlbA)
BHO: D560_1328
BHM: D558_1317
BHZ: ACR54_00110(gfo)
BTRM: SAMEA390648701342(bplA)
BPDZ: BBN53_20140
AXY: AXYL_06286
AXN: AX27061_5896
AXX: ERS451415_06023(gfo)
AIS: BUW96_24710
ASW: CVS48_07140
TEQ: TEQUI_1006
TEA: KUI_0407
TEG: KUK_0147
AAMM: FE795_15360
ODI: ODI_R2826
OUE: I6G29_01505
PNA: Pnap_3129
POS: DT070_03600 DT070_14460
POO: F7R28_05840 F7R28_16145
AJS: Ajs_3015
ACK: C380_07385
ACIP: CBP36_03010
ACIS: CBP35_15930
AAV: Aave_0950
AMON: H9L24_09495
DLA: I6G47_27630
VAP: Vapar_1927
VPE: Varpa_4688
VPD: VAPA_1c53890
CTES: O987_08010
CSER: CCO03_06555
COF: FOZ74_09545
HYB: Q5W_21470
HYL: LPB072_07145 LPB072_22690
RGE: RGE_41570(bplA)
RBN: RBXJA2T_06710
RDP: RD2015_4065
ROI: N4261_22140
KIA: G8A07_07045
PKT: AT984_02045
PAQA: K9V56_016895
MIU: ABE85_17725
SNN: EWH46_01090
IDC: LRM40_05260
ATER: MW290_27430
LCH: Lcho_0289
RGU: A4W93_23595
JAH: JAB4_049950(iolG_2)
HSE: Hsero_4195
HSZ: ACP92_20960
HFR: G5S34_02285
MASW: AM586_10905
MASS: CR152_27235
MANC: IV454_20540
MFY: HH212_25110
MVAR: MasN3_21780(wlbA)
MLIR: LPB04_23365 LPB04_23900
DZO: SR858_15685
TMJ: P0M04_31025
NOK: FAY22_12115
TTW: LCC91_03250
ETB: N7L95_14855
BBAY: A4V04_01330
APP: CAP2UW1_0065
NAF: GQ61_06800
MESP: C1M53_04250
MES: Meso_4484
NIY: FQ775_09675
PMOB: HG718_00085
SMK: Sinme_4777
SMQ: SinmeB_3736
SMX: SM11_pD0667
SMI: BN406_05730
SMEG: C770_GR4pD0650
SMEL: SM2011_b21355
SMER: DU99_28765
SMD: Smed_4750
SAME: SAMCFNEI73_pC1037
SINO: SS05631_b57670
EMX: FKV68_31770
EGI: PZN02_004925
SKM: PZL22_000186
STEG: QA637_21005
AGC: BSY240_4564
REP: IE4803_CH00778
RLE: RL0824
RGA: RGR602_CH03041
RHK: Kim5_CH00859
RSUL: N2599_13345
ARO: B0909_16745
NGG: RG540_PA12740
NEN: NCHU2750_04910
RHT: NT26_2973
RFV: RFYW14_03055
BJU: BJ6T_32920
BJP: RN69_15965
BRS: S23_22680
BIC: LMTR13_10760
BRK: CWS35_31765 CWS35_31850
BGQ: X265_13695
BGZ: XH91_11630
BBET: F8237_26405
BARH: WN72_33195
BEL: BE61_40460
BSEP: HAP48_0047530 HAP48_0047655
BQB: J4P68_0000015 J4P68_0006710 J4P68_0006830
BSEI: KMZ68_19050
BBAN: J4G43_038005
BAUT: QA635_15510 QA635_15625
BBRA: QA636_16015 QA636_16145
BGK: IC762_24815
BPAH: QA639_29435 QA639_29555
BROS: QUH67_25950
TALZ: RPMA_09995
BVES: QO058_11155
ANC: GBB76_09925
HNI: W911_00400
DEQ: XM25_13460
DEA: FPZ08_13280
DOY: JI749_13300
YTI: FNA67_17200
RUA: D1823_06620
RUT: FIU92_10720(pht2)
RCON: K3740_17735
RPON: G3256_01625
OTM: OSB_21250(gfo_3)
SULI: C1J05_06025
SPOT: G6548_17115
SFAV: PL335_17210
TOM: BWR18_15515
OCD: FHY55_10395
PARO: CUV01_03365
PTP: RCA23_c02930
THW: BMG03_04755
PALW: PSAL_034710(apsD_1)
LVR: T8T21_17100
FAQ: G5B39_12330
SPHK: SKP52_10585
SPHQ: BWQ93_05585
SPHO: C3E99_07010
SPLM: BXU08_19465
SSIN: G7078_06195
SCAB: LZK98_15415
SHAN: PPZ50_18400
SPHL: LPB140_06435
SPHS: ETR14_12065
SFLV: IC614_08685
ELI: ELI_13345
ERR: DVR09_11395
EBLA: JGUZn3_12530(iolG_2)
AZM: DM194_14155
MGRY: MSR1_31310(ycjS_1)
MAGX: XM1_0970
DVN: HQ394_13385
MAG: amb0131
THAI: IT893_15695
MAGQ: MGMAQ_3670
MGM: Mmc1_2424
PEG: E5R92_03420
APC: HIMB59_00015070
APM: HIMB5_00011140
PAQI: KW060_14930
HEO: C694_03500
HPJ: jhp_0620
HPA: HPAG1_0661
HPS: HPSH_03470
HHP: HPSH112_03620
HHQ: HPSH169_03465
HHR: HPSH417_03260
HPG: HPG27_637
HPP: HPP12_0690(wbpB)
HPB: HELPY_0692
HPL: HPB8_881(wbpB)
HPC: HPPC_03400
HCA: HPPC18_03315
HPM: HPSJM_03455
HPE: HPELS_03135
HPO: HMPREF4655_20921
HPI: hp908_0688(wbpB)
HPQ: hp2017_0665(wbpB)
HPW: hp2018_0666(wbpB)
HPU: HPCU_03650
HEF: HPF16_0688(wbpB)
HPF: HPF30_0654(wbpB)
HEQ: HPF32_0643(wbpB)
HEX: HPF57_0700(wbpB)
HPT: HPSAT_03405
HPZ: HPKB_0669
HPV: HPV225_0684
HPX: HMPREF0462_0737
HEN: HPSNT_03505
HPH: HPLT_03380
HEG: HPGAM_03495
HPN: HPIN_03255
HEP: HPPN120_03320
HEU: HPPN135_03335
HES: HPSA_03225
HPYS: HPSA20_0708
HCN: HPB14_03300
HPD: KHP_0646(wbpB)
HEY: MWE_0830(wbpB)
HER: C695_03505
HEI: C730_03505
HPYA: HPAKL117_03210
HPYK: HPAKL86_04340
HPYO: HPOK113_0689(wbpB)
HPYL: HPOK310_0668(wbpB)
HPYB: HPOKI102_03625
HPYC: HPOKI112_03660
HPYD: HPOKI128_03220
HPYE: HPOKI154_03450
HPYF: HPOKI422_03630
HPYG: HPOKI673_03435
HPYH: HPOKI828_03435
HPYJ: HPOKI898_03630
HPYR: K747_07485
HPYI: K750_05685
HPYU: K751_03995
HPYM: K749_02110
HEM: K748_00585
HEB: U063_0983
HEZ: U064_0987
HHE: HH_1662(wbpB)
HAC: Hac_0861(wbpB)
HMS: HMU06630
HFE: HFELIS_04170
HBI: HBZC1_15200
HCE: HCW_05405
HCM: HCD_05220
HCP: HCN_0856(wbpB)
HCB: HCBAA847_1124(wbpB)
HHM: BN341_16330
HAD: CDV25_01305 CDV25_01335
HET: BBW65_01175
HCL: NCTC13205_00267(ycjS)
HWI: A0Z60_07530
HSH: NHP194022_04680
HPUL: NCTC13154_00522(ycjS_1)
HAIL: ASB7_01280
WSU: WS2188(WBPB)
TDN: Suden_1422
SULG: FJR48_03715
SPAL: FM071_05905
SMAX: FJR03_06645
SAQT: GJV85_04705
CCO: CCC13826_0542
CBLA: CBLAS_0711
ABU: Abu_0662
ALAN: ALANTH_0830
ANT: Arnit_2570
AAQI: AAQM_2034
ASUI: ASUIS_2001
PACO: AACT_0950
AHS: AHALO_0814
HBV: ABIV_0864
SUN: SUN_0093
SINU: IMZ28_10360
GEB: GM18_1433
GLO: Glov_1510
TAMM: GEAMG1_2516(wbpB)
GER: KP004_12105
GNT: KP003_11600 KP003_17840
GPL: M1B72_07915
GSB: GSUB_15340
GHC: L9S41_10670
PEF: A7E78_01465
PSYF: N1030_13690
DSB: LN040_10510
LIP: LIC097
LIR: LAW_30095
DBA: Dbac_3255
DEO: CAY53_06145
DOL: Dole_1819
DAL: Dalk_1674
TOP: TOPB45_1236
TCM: HL41_05485
THET: F1847_01380
CTHI: THC_1547
TMAI: FVE67_05410
PABO: BCY86_02080
BSED: DN745_14955
PCAY: FRD00_13475
BBAE: FRD01_13735
BBAT: Bdt_1672
BBAC: EP01_04555
BDC: DOE51_07880
BREY: MNR06_04710
SBF: JCM31447_25090
BLI: BL03076
BLD: BLi00809(yrbE)
BLH: BaLi_c09130(yrbE)
BSON: S101395_01005(bvdR)
BIF: N288_23270
BMET: BMMGA3_15120
BGY: BGLY_0828
BWH: A9C19_10500
BSAF: BSL056_02015
BFD: NCTC4823_03739(gfo)
BACI: B1NLA3E_20885
BACW: QR42_02065
BACQ: DOE78_22820
BCOH: BC6307_01160
BCIR: C2I06_01615 C2I06_02230 C2I06_13815
BEO: BEH_14640
BCL: ABC0605
BLE: BleG1_2898
BON: A361_24880
CSUA: IM538_21385
CFIR: NAF01_22650
CSOA: LIS82_24415
BDA: FSZ17_21485
OCN: CUC15_17145
OCB: CV093_18425
GKA: GK3166
GTE: GTCCBUS3UF5_35350
GTK: GT3570_15455
GTM: GT3921_03250
BCAL: CWI35_12090
GYC: GYMC61_3257
GYA: GYMC52_3288
GCT: GC56T3_3177
GGH: GHH_c32410
GEL: IB49_07995
GSE: GT50_07690
GEJ: A0V43_13695
GZA: IC807_11900
PTB: DER53_03275
AAMY: GFC30_481
AXL: AXY_03830
LYG: C1N55_07270
HHD: HBHAL_2426
VIG: BKP57_04850
VIL: CFK37_01455 CFK37_01460
VNE: CFK40_17645
VPT: KBP50_03840
FAR: ABE41_017785
BMUR: ABE28_003935
PSYH: D0S48_07970
PSYO: PB01_04620
GRC: GI584_05185 GI584_07220
POF: GS400_13830
MEKU: HUW50_20990
AIA: AWH56_015925
BLEN: NCTC4824_00366(yvaA_1) NCTC4824_00367(ycjS_1) NCTC4824_01177(ycjS_5)
SEDD: ERJ70_04170 ERJ70_06670
BVQ: FHE72_22055
BVJ: I5776_14050
BOU: I5818_17210
GAJ: MY490_11980
MSUT: LC048_00250
SSP: SSP1334
SXY: BE24_04425
SXL: SXYLSMQ121_1372
SXO: SXYL_01457
SEQO: SE1039_12560
SCOH: BZ166_11260
SNL: BJD96_07230
SPSD: JMB28_07585
SURY: MUA21_05830
SEDA: MNY58_07475
STAP: AOB58_517
PJD: Pjdr2_4073
GYM: GYMC10_1211
PLV: ERIC2_c20090
PGM: PGRAT_15295
POD: PODO_28500
PAEN: P40081_17815
PAEF: R50345_14270
PAEQ: R50912_16610
PAEA: R70723_15265
PAEE: R70331_24850
PAEH: H70357_16925
PAEJ: H70737_13620 H70737_15725
PBJ: VN24_11935
PIH: UB51_13970
PSON: JI735_24145
PNP: IJ22_38360 IJ22_49060
POW: IJ21_32520 IJ21_43900
PYG: AWM70_20130
PDH: B9T62_11895
PIB: BBD41_08725
PCX: LPB68_18930
PVO: PVOR_08105
PLW: D5F53_23505
PPSC: EHS13_28630
PLUT: EI981_18335 EI981_27145
PALB: EJC50_27535 EJC50_29195
PCHI: PC41400_04320
PBK: Back11_15410 Back11_63550
PRZ: GZH47_11580 GZH47_17545 GZH47_31940
PLYC: GXP70_05125 GXP70_06580 GXP70_28940
PAUN: MJA45_15150
PKP: SK3146_05620(gfo_3)
TCO: Theco_3205
ANX: ACH33_01670
ATHE: K3F53_17345
PKU: AUO94_04055
PMAR: B0X71_16965 B0X71_16970
NTR: B0W44_04610
LFB: C1X05_09310 C1X05_16015
TVU: AB849_005520
KPUL: GXN76_15355
KEB: GXN75_16715
PABS: JIR001_23250 JIR001_30150
SPAB: KQ224_02975
ECAS: ECBG_00089
VCP: H9L18_01905
AUI: APT62_02655
AUH: AWM75_03250
CRN: CAR_c21330
JAR: G7057_03175
JPO: G7058_07610 G7058_08180
CTC: CTC_02264
CTET: BN906_02465
CNO: NT01CX_1781
CBA: CLB_3136
CBH: CLC_3009
CBY: CLM_3513
CBL: CLK_2501
CBK: CLL_A3174
CBB: CLD_1433
CBI: CLJ_B3373
CBN: CbC4_0993
CBT: CLH_2923
CBF: CLI_3166
CBM: CBF_3155
CBJ: H04402_03184
CBE: Cbei_4619
CBZ: Cbs_4619
CBEI: LF65_05162
CKL: CKL_3168
CKR: CKR_2806
CLJ: CLJU_c34090
CSR: Cspa_c53470
CPAS: Clopa_4712
CSB: CLSA_c41240(yrbE2)
CAH: CAETHG_1307
CSQ: CSCA_4789
CLD: CLSPO_c32020
CCK: Ccar_17270
CBUT: ATN24_15725
CTYK: CTK_C08660
CEU: A7L45_12160
CTAE: BGI42_12580
CARG: RSJ17_08110
CDRK: B9W14_20925
CDY: F3K33_23515
CCOH: SAMEA4530647_1933(ycjS)
CFER: D4Z93_04405
CGAS: J1C67_09890 J1C67_19005
CLOS: DMR38_17085
CNN: CNEO_4194
CGEL: psyc5s11_49910
CTAG: LL095_12355
CTHD: CDO33_08210 CDO33_08265
HHW: NCTC503_02000(afr)
CALE: FDN13_03435
CLO: HMPREF0868_0599
FSA: C5Q98_06705
RBP: B6259_08165
RHER: EHE19_018995
CCEL: CCDG5_0711
FPLA: A4U99_06465
EHA: Ethha_0671
FPR: FP2_24960
FPRA: CG447_01245
FDU: GXM22_07620
OBJ: EIO64_14100
CAML: H6X83_09695
CLF: GJQ69_02335
CARL: PXC00_03590
CAPR: EQM14_12870
CFEM: HCR03_17325
SWO: Swol_0706
DSY: DSY3345
DHD: Dhaf_4503
DDH: Desde_3864
DDL: Desdi_3236
DMT: DESME_14510
SGY: Sgly_3009
DOR: Desor_5337
DAI: Desaci_4448
DMI: Desmer_4338
DED: DHBDCA_p2685
DEC: DCF50_p2696
DRS: DEHRE_13250
PTH: PTH_1113(MviM)
TFR: BR63_12295
ELM: ELI_2560
EMT: CPZ25_005080
SAY: TPY_3674
SAP: Sulac_3373
STHR: BXT84_14985
EUU: ADJ67_02465
BPB: bpr_I0406
BYL: A4V09_01925 A4V09_19545
BPRO: PMF13cell1_01643(gfo_1) PMF13cell1_05065(iolX_4) PMF13cell1_05439(gfo_4)
CSH: Closa_0342
CASP: NQ535_09290
VGU: HYG85_03210 HYG85_08055 HYG85_13860
VPY: HZI73_04125 HZI73_21530 HZI73_24085
MDV: C5Q96_07730
AMT: Amet_3444
ROC: HF520_12270 HF520_12275
CST: CLOST_2336
TTE: TTE0653(MviM2)
TIT: Thit_0178
TMT: Tmath_0235
TKI: TKV_c06640(mviM)
TSH: Tsac_0498
MAS: Mahau_0353 Mahau_1490
TEP: TepRe1_1590
TAE: TepiRe1_1712
TOC: Toce_1590
HALS: D7D81_05130
AAR: Acear_2129
HHL: Halha_0117
CSC: Csac_0599 Csac_1804
ATE: Athe_1239 Athe_2334
COB: COB47_1317 COB47_2107
CHD: Calhy_0192 Calhy_1486
COW: Calow_1030 Calow_2063
CKI: Calkr_1220 Calkr_2363
CLC: Calla_0086 Calla_0628
CKN: Calkro_0219 Calkro_1461
CCHA: ELD05_07305 ELD05_12070
CDIA: CaldiYA01_01930 CaldiYA01_12690
CNAG: OTJ99_000371 OTJ99_001498
CMOR: OTK00_001390
CDAN: SOJ16_001196 SOJ16_002463
FMA: FMG_0585
SPOA: EQM13_10605
PUF: UFO1_0304
LPIL: LIP_1016
TBM: BK010_04830
TBZ: BK011_02340 BK011_09435
ELE: Elen_0638
CGB: cg2918
CGU: WA5_2546
CGT: cgR_2455 cgR_2540
CGS: C624_12525 C624_12960
CGG: C629_12530 C629_12965
CGM: cgp_2918
CGJ: AR0_12795
CGQ: CGLAR1_12660
CGX: SB89_12425
CGY: CGLY_11570
CDO: CDOO_09605
CUT: CUTER_00580
CSTA: CSTAT_03290
CCJZ: ccrud_11890
CAMG: CAMM_03405
CSUR: N24_2630 N24_2719
CCYS: SAMEA4530656_1528(gfo)
CCYC: SCMU_39910
BFV: C628_13055
RER: RER_46960
REY: O5Y_22175
REB: XU06_22290
RQI: C1M55_23630
ROP: ROP_15350
ROA: Pd630_LPD06020
RRZ: CS378_14825
RHOD: AOT96_03665
RKO: JWS14_09505
RGO: KYT97_30395
ROZ: CBI38_24870
RPSK: JWS13_36330
SCI: B446_01935 B446_33355
SCX: AS200_44420
SCAD: DN051_42370
SALU: DC74_7991
SALL: SAZ_41245
SVN: CP980_33425
SSEO: D0Z67_01125
SMOB: J7W19_27470
LXX: Lxx17360(bplA)
LXY: O159_19880
LEIF: HF024_02130
LSE: F1C12_00010
CMI: CMM_2271
CMH: VO01_10570
CMS: CMS2465
CMC: CMN_02246
CCAP: AES38_11080
MPRT: ET475_07805
MOY: CVS54_03687(iolX)
CUM: NI26_03705
CUB: BJK06_03895
CUG: C1N91_03560
CCIT: QPK07_03855
FRP: AX769_09535
FSB: GCM10025867_26300
AGF: ET445_08965
MSPO: KXZ72_13600
HUW: FPZ11_06520
GRY: D7I44_03310
PLAP: EAO79_04425
GLN: F1C58_16425
NAEI: GCM126_04470
ART: Arth_0500 Arth_3483
ARR: ARUE_c04960
ARM: ART_1531
ARL: AFL94_05080
ARE: AL755_16035
AAQ: AOC05_10420
ARW: MB46_11180
ARH: AHiyo8_29850 AHiyo8_52300
ARY: ATC04_12805
ARZ: AUT26_02220
ARQ: BWQ92_13480
ARN: CGK93_02805 CGK93_19165
ARX: ARZXY2_3410
ARTH: C3B78_03100
ARTP: E5206_01110
ACIT: HPK19_06430
AOD: Q8Z05_04365 Q8Z05_10450
ARI: UM93_15235
AAU: AAur_0525
PUE: FV140_02760
PNV: JMY29_02410 JMY29_13015
ACH: Achl_0779
APN: Asphe3_06760
PSUL: AU252_07695 AU252_09955
PSNI: NIBR502771_01505
PSEY: GU243_18880
PDEL: JCQ34_03065
POK: SMD14_03345
GPR: JQN66_05520
SATK: SA2016_0412 SA2016_3913
BCV: Bcav_3315 Bcav_3348
BFA: Bfae_01870
BRV: CFK39_09080
BGG: CFK41_16260
BRZ: CFK38_01740
BSAU: DWV08_15020
BRR: C1N80_02130
IVA: Isova_2543
CCEU: CBR64_12280
CPRT: FIC82_017840
PSEI: GCE65_04230
GEZ: FE251_10180
HALT: IM660_02185 IM660_02195 IM660_11160
RHAL: LQF10_01950
MPH: MLP_05720
MIK: FOE78_01370
MICG: GJV80_16690 GJV80_18860
RAIN: Rai3103_13930
PRV: G7070_05670 G7070_06850
MGG: MPLG2_3178
KSL: OG809_21985
SACE: GIY23_12090
MPRN: Q3V37_14190
ACTN: L083_1494 L083_6344
AFS: AFR_16830
PLAB: C6361_08510
PLAT: C6W10_05080
ATL: Athai_37850
DVC: Dvina_14965
CCAZ: COUCH_19560
RUB: GBA63_02070
SYNW: SynWH8103_00503
PMI: PMT9312_1300
PMB: A9601_14101
NCN: BZZ01_20160
RRS: RoseRS_2681
RCA: Rcas_2202
ABAO: BEQ56_06830
KBS: EPA93_43700
TTR: Tter_0217 Tter_1908
DPD: Deipe_2030
DSW: QR90_12655
DEIN: DAAJ005_05030
DRD: LMT64_11840
DRB: N0D28_10075
TRA: Trad_1846
TTH: TT_C0287(wbpB)
MRB: Mrub_0358
MRE: K649_01410
MTAI: Mtai_v1c25020
FGI: OP10G_3931
OTE: Oter_0898
OBG: Verru16b_02254(afr_3)
OBT: OPIT5_15870 OPIT5_24765
CAA: Caka_2925
MTAR: DF168_01774(gfo_3)
LUO: HHL09_22720
VBA: IMCC26134_03350
RBA: RB6199
PSL: Psta_2822 Psta_3167
PIR: VN12_21635(afr_4)
RUL: UC8_06010(wbpB_1) UC8_10100(gfo_3) UC8_50390(wbpB_2)
MFF: MFFC18_27070(gfo_4)
ROL: CA51_12660(gfo_3)
RUV: EC9_19640(pht4_1)
RCF: Poly24_12390(pht4_1)
AHEL: Q31a_45900(ycjS_2)
LCRE: Pla8534_38000(afr_6) Pla8534_38530(gfo_6) Pla8534_69440(wbpB)
AAGG: ETAA8_64750(afr_6)
BVO: Pan97_25430(gfo_5)
BREM: PSR63_26790
RLC: K227x_30360(pht4)
SMAM: Mal15_56990(pht4)
SNEP: Enr13x_24690(afr_2)
TTF: THTE_2673
LPAV: PLANPX_2245
LLH: I41_20060(gfo_2)
AMUC: Pan181_17760(afr_1)
PND: Pla175_16240(ycjS)
AMOB: HG15A2_31400(wbpB)
PLM: Plim_2198
PEH: Spb1_29720(afr_3)
PBS: Plabr_1624 Plabr_2773
PLS: VT03_19395(afr_3)
PLH: VT85_17850(gfo_3)
FMR: Fuma_06237(afr_5)
GMR: GmarT_05450(afr_1)
GIM: F1728_11525
GPN: Pan110_05850(afr_2)
GFM: Enr17x_06990(afr_1)
MRI: Mal4_34820(afr_7)
SDYN: Mal52_02280(gfo_2)
PLON: Pla110_21360(afr_3)
ACAF: CA12_39650(afr_4)
SVP: Pan189_28170(afr_2)
TPOL: Mal48_22940(afr_2)
CHYA: V22_09580(afr_1)
CCOS: Pan44_07040(afr_2)
PVAR: SH412_004455
CCOP: Mal65_22430(gfo_2)
GES: VT84_01060(gfo_1) VT84_03575(ycjS)
GOG: C1280_16480 C1280_30365
GMS: SOIL9_74650 SOIL9_83510
TIM: GMBLW1_10240
LRS: PX52LOC_02889
FTJ: FTUN_3203 FTUN_8198
ULI: ETAA1_50810(gfo_7)
TSPH: KIH39_13880
IPA: Isop_0786
SACI: Sinac_5779 Sinac_6114
PBOR: BSF38_01063(gfo_2) BSF38_03488(gfo_6)
AGV: OJF2_28930(gfo_7)
PBAS: SMSP2_00900(ycjS_4) SMSP2_01883(wbpB)
ALUS: STSP2_02795(wbpB)
LPRO: PQO03_15080
TPED: TPE_0183
TRM: JO41_03150
TRZ: GWP43_02810
TPAV: HRQ91_00985 HRQ91_10790
TMED: DWB79_01420
TRP: ABH09_02750
SSM: Spirs_3603
STA: STHERM_c06180
STQ: Spith_0632
SPER: EW093_13200 EW093_13430
SLR: L21SP2_3140
OCK: EXM22_01585
SBU: SpiBuddy_0091
SGP: SpiGrapes_1443 SpiGrapes_1792 SpiGrapes_2991
TAZ: TREAZ_2637
SCD: Spica_2851
LKM: EFP84_18045
TPX: Turpa_0310
ABA: Acid345_3316
SUS: Acid_1518
PFER: IRI77_04535
ABAC: LuPra_02895(afr_4)
LUB: TBR22_A52970
GEP: Q9293_00420
FUS: HMPREF0409_01480
FNE: FSDG_01878
FHW: RN87_00945
FCI: I6I83_02410
STR: Sterm_4053
CPOR: BED41_09420
ACO: Amico_1727
TLI: Tlie_1823
GAU: GAU_1966
GPH: GEMMAAP_10215
GGR: HKW67_04500
GBA: J421_2473
BUN: Bun01g_30810
PGI: PG_2119
PGN: PGN_0168(wbpB) PGN_1068
PGT: PGTDC60_1302
PAH: Poras_0234
PCRE: NCTC12858_00136(iolG)
PEND: LA319_05660
PMUC: ING2E5A_0875 ING2E5A_0880(iolX1)
PET: PEIBARAKI_4689
PPN: Palpr_0599
PDI: BDI_2789
PARC: CI960_20185
PMER: INE87_02436
PGOL: K6V26_21195
PJO: LK449_17465
PFAI: NXY11_20085
TFO: BFO_1077
TOH: BCB71_10490
PII: NF347_12995
OSP: Odosp_0961
BVIR: I6J59_09245 I6J59_14365
BFH: F1611_03130
TTZ: FHG85_08190
BLQ: L21SP5_01622(wbpB)
BACC: BRDCF_p620(ycjS) BRDCF_p621
DORI: FH5T_09010 FH5T_09100 FH5T_21445
DRC: G0Q07_00780 G0Q07_02715
MCOS: GM418_10500 GM418_12515 GM418_23735
ASX: CDL62_08695
ALKQ: M9189_00215
CBAE: COR50_03165
CHOR: MKQ68_20320
NKO: Niako_6748
NSO: NIASO_01490
NIA: A8C56_08560
FLA: SY85_01720
FGG: FSB75_02855 FSB75_06700 FSB75_11455
ARB: A9P82_11335
AGI: FSB73_17185
ATEE: K9M52_16130
ARAC: E0W69_017455
PSEG: D3H65_09815
PGIN: FRZ67_02960 FRZ67_02965
PGO: FSB84_21450
FLS: GLV81_01885
LACS: H4075_01935
FLP: LK994_08750
FLC: KJS93_05830
FLV: KJS94_04580 KJS94_16535
HHY: Halhy_2761
SGN: SGRA_4064
PHE: Phep_0349 Phep_0551
PEJ: FYC62_11505
PSN: Pedsa_1140 Pedsa_3258
SPSC: E2P86_16385
SPHE: GFH32_12500
SCN: Solca_3168
SLAS: L2B55_17120
MGIK: GO620_005155
SBX: CA265_19285
CMR: Cycma_4733
CAMU: CA2015_4545
EVI: Echvi_3098
EST: DN752_22330
ECHI: FKX85_14665 FKX85_20315
ALM: AO498_00110
SLI: Slin_4507
SRD: SD10_24330
SMON: AWR27_24625
SPIR: CWM47_04730
SPIK: EXU85_28890
SPIB: G8759_06370 G8759_15345
STAE: HNV11_19265
SRHO: HH216_10170
SOQ: LQ777_03620 LQ777_26125
SFOL: H3H32_25115
SENF: GJR95_05965 GJR95_09775
RSI: Runsl_3956
RUN: DR864_23540
FAE: FAES_5182
FIB: A6C57_06070
HSW: Hsw_1635
HYM: N008_00290
HYD: PK28_08405
HYE: AM218_07895
HYG: AUC43_12620
HYP: A0257_01145
HYZ: AXW84_10805
HNV: DDQ68_04740
HYH: D3Y59_06270
HYJ: FHG12_00250
HQI: H9L05_19910
HRS: HER32_18390
HBN: GUY19_05570
HTS: HMJ29_15375
HMT: MTP16_20420
HTB: MTX78_09015
HYK: O9Z63_05260
HSK: H4317_11580
HCW: O3303_03490
HSB: MWH26_06175
HAEI: MUN82_10460
HCU: MUN79_16575
HVL: MUN86_08610
HCF: MUN80_14975
RUF: TH63_05750
RTI: DC20_16625
RUD: TH61_13615
NIB: GU926_01120
FPF: DCC35_01150
FKA: KM029_13880
FBT: D770_17580 D770_17610
CHRW: KA713_13995
CHK: D4L85_11150
FUV: JR347_14480
TPEL: P0M28_09285
FBR: FBFL15_1030
CAPH: CGC49_04835
RBI: RB2501_00856
ZGA: ZOBELLIA_1140 ZOBELLIA_1740(wbpB)
ZLA: Q5W13_08580
NMF: NMS_1392
POM: MED152_05725
POB: LPB03_07140
PRN: BW723_09650
POLA: BXQ17_13895
POA: CW731_08025
PHAL: H9I45_06505
PLIT: K8354_09870
PPEC: H9W90_01185
PBAT: JL193_14510
PCEA: J3359_17210
PUN: NQP51_08280
PHG: KCTC32516_01449(wbpB)
AHZ: APS56_00715
TDI: AUW17_02345
TEN: LPB136_06615
TJE: TJEJU_1135(wbpB)
TMAR: MARIT_2536(wbpB)
TMP: F9Y86_04690
TOV: PG911_16305
TRT: PG912_10895
TFI: PJJ26_03005
TSIG: D6T69_05605
LUT: Lupro_06250
LUL: LPB138_01540
WFU: AXE80_01025
SALT: AO058_00385
AQB: D1818_09115
AQA: D1815_20985
AQD: D1816_16185
EMAR: D1013_01180 D1013_17800
PSYN: E9099_06905
MGEL: G5B37_01375
GAA: HX109_12625 HX109_13045
ASAG: FGM00_16580
SPON: HME9304_01540(wbpB)
FBE: FF125_12120
LUY: QZH61_06860
RAN: Riean_1174
RAI: RA0C_1443
RAR: RIA_1052
RAG: B739_0706
RAE: G148_0432
RAT: M949_1164
WVI: Weevi_1284
CIH: ATE47_11365
CHH: A0O34_13950
CIO: CEQ15_13535
CHRZ: CO230_02295
CARH: EGY05_16495
CGLE: NCTC11432_02321(ycjS)
CLAC: EG342_00040
CTAK: 4412677_01091(yvaA)
CSAL: NBC122_00346(iolW_1)
CNP: M0D58_15450
CCAB: PFY12_05475
CHRJ: CHRYMOREF3P_1890
CHRA: F7R58_09215
CHRC: QGN23_07160
CCAS: EIB73_13630
CBAU: H1R16_04010
EBV: F0358_05705
EFAL: FH779_00830
ESTE: HNV03_10880
BPOR: BPO_1679
APIB: G8C43_06600
CIV: IMZ16_09065
FBO: J9309_04135
FTE: Fluta_2062
FLU: CHH17_01450
OHO: Oweho_3295
CHYD: H4K34_02510
SHYR: LA303_13210
BBAU: AEM51_05415 AEM51_07995
RMR: Rmar_1674
RMG: Rhom172_1112
RBAR: AWN76_001865
IAL: IALB_2460(wbpB)
MRO: MROS_2688
CPRV: CYPRO_3324
CACI: CLOAM1565(mviM)
SAF: SULAZ_0344
TMM: Tmari_0583
TMI: THEMA_01740
TMW: THMA_0600
TMQ: THMB_0600
TMX: THMC_0600
TPT: Tpet_0333
TNP: Tnap_0367
TRQ: TRQ2_0351
TNA: CTN_0079
THQ: T2812B_01745
THZ: CELL2_01820
THR: TRQ7_01865
TLE: Tlet_0884
TTA: Theth_0520
PHY: AJ81_09400
TME: Tmel_1052
TAF: THA_1334
THP: BG95_05995
THER: Y592_06070
TFE: JYK00_03495
FNO: Fnod_1779
FPE: Ferpe_2053
FIA: NA23_10385
FRR: IB67_00060
OCY: OSSY52_04570
PMO: Pmob_0962
MPZ: Marpi_1464
MARN: LN42_07805
MAEO: JRV97_06355
DTN: DTL3_0340
KOL: Kole_1641
KPF: IX53_00290
MPG: Theba_1179
MINF: MESINF_2243
ASAC: ATHSA_0559
CNI: Calni_1806
CABY: Cabys_972
SCHV: BRCON_0933
FSH: Q2T83_00705 Q2T83_02475
HALR: EFA46_010675
HUT: Huta_2849
HTI: HTIA_2755
HRR: HZS55_01030 HZS55_02890 HZS55_22175
HPEL: HZS54_01075 HZS54_02610 HZS54_25835
HLT: I7X12_10350 I7X12_14360
HGI: ABY42_15230
HTU: Htur_4428
HSAL: JMJ58_23625
HXA: Halxa_0374 Halxa_0397
HLR: HALLA_00600 HALLA_04470
SSO: SSO3049
SSOA: SULA_0826
SSOL: SULB_0828
SSOF: SULC_0826
SSHI: J5U23_00438
SIS: LS215_2481
SIA: M1425_2309
SIM: M1627_2388
SID: M164_2311
SIY: YG5714_2446
SIN: YN1551_0464
SII: LD85_2596
SIH: SiH_2250
SIR: SiRe_2194
SIC: SiL_2159
SULA: BFU36_07240
SULE: GFS03_12445
SACD: HS1genome_1651
CMA: Cmaq_0434
 » show all
Reference
1  [PMID:19282284]
  Authors
Westman EL, McNally DJ, Charchoglyan A, Brewer D, Field RA, Lam JS
  Title
Characterization of WbpB, WbpE, and WbpD and reconstitution of a pathway for the biosynthesis of UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid in Pseudomonas aeruginosa.
  Journal
J Biol Chem 284:11854-62 (2009)
DOI:10.1074/jbc.M808583200
  Sequence
[pae:PA3158]
Reference
2  [PMID:19348502]
  Authors
Larkin A, Imperiali B
  Title
Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: enzymes in the Wbp pathway responsible for O-antigen assembly in Pseudomonas aeruginosa PAO1.
  Journal
Biochemistry 48:5446-55 (2009)
DOI:10.1021/bi900186u
  Sequence
[pae:PA3158]
Reference
3  [PMID:20690587]
  Authors
Thoden JB, Holden HM
  Title
Structural and functional studies of WlbA: A dehydrogenase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid .
  Journal
Biochemistry 49:7939-48 (2010)
DOI:10.1021/bi101103s
  Sequence
[pae:PA3158]
Reference
4  [PMID:21241053]
  Authors
Thoden JB, Holden HM
  Title
Biochemical and structural characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: enzymes required for the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid.
  Journal
Biochemistry 50:1483-91 (2011)
DOI:10.1021/bi101871f
  Sequence
[bpe:BP0093] [cvi:CV_4127]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.335
IUBMB Enzyme Nomenclature: 1.1.1.335
ExPASy - ENZYME nomenclature database: 1.1.1.335
BRENDA, the Enzyme Database: 1.1.1.335

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   KEGG ORTHOLOGY (2)   
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   UniProt (140)   
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   RefSeq(nuc) (1592)   
   GenBank (219)   
   EMBL (204)   
Protein domain (4)   
   InterPro (4)   
All databases (18701)   

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