KEGG ENZYME: 1.1.1.361

ENZYME: 1.1.1.361

Entry

EC 1.1.1.361                Enzyme

Name

glucose-6-phosphate 3-dehydrogenase;
ntdC (gene name)

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

D-glucose-6-phosphate:NAD+ oxidoreductase

Reaction(IUBMB)

D-glucose 6-phosphate + NAD+ = 3-dehydro-D-glucose 6-phosphate + NADH + H+ [RN:R10519]

Reaction(KEGG)

R10519

Substrate

D-glucose 6-phosphate [CPD:C00092];
NAD+ [CPD:C00003]

Product

3-dehydro-D-glucose 6-phosphate [CPD:C20668];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

The enzyme, found in the bacterium Bacillus subtilis, is involved in a kanosamine biosynthesis pathway.

History

EC 1.1.1.361 created 2013

Pathway

ec00998

Biosynthesis of various antibiotics

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K18652

glucose-6-phosphate 3-dehydrogenase

Genes

ECV:	APECO1_O1CoBM84

YEL:	LC20_02631

PQU:	IG609_015980

EAM:	EAMY_0625(yhjJ1)

EAY:	EAM_2805(ntdC)

EPY:

EpC_29580

EPR:	EPYR_03199(yhjJ)

ERJ:	EJP617_17780

RHEY:

FEE42_05000

BSU:	BSU10530(ntdC)

BSR:

I33_1187

BSL:

A7A1_3681

BSH:	BSU6051_10530(ntdC)

BSY:	I653_05325

BSUT:

BSUB_01150(ntdC)

BSUL:

BSUA_01150(ntdC)

BSUS:

Q433_05960

BSO:	BSNT_07497(yhjJ)

BSN:	BSn5_17150

BSQ:	B657_10530(ntdC)

BSX:

C663_1077

BSP:	U712_05380

BSS:	BSUW23_05340(ntdC)

BST:

GYO_1357

BIT:	BIS30_15975

BLI:	BL03982(ntdC)

BLD:	BLi03944(ntdC)

BLH:	BaLi_c39590(ntdC)

BSON:

S101395_00445(ntdC) S101395_00446

BHT:	DIC78_04340

BMOJ:

HC660_11090(ntdC)

BTEQ:

G4P54_05585

BAN:

BA_3280

BAR:

GBAA_3280

BAT:

BAS3045

BAH:	BAMEG_1341

BAI:

BAA_3320

BAX:	H9401_3122 H9401_3123

BANR:

A16R_33410

BANS:

BAPAT_3140

BANH:

HYU01_16115

BANV:

DJ46_2021

BCU:	BCAH820_3271

BCX:

BCA_3324

BCF:

bcf_16040

BTL:

BALH_2923

BTHT:

H175_233p028

BTW:

BF38_4420

BWD:	CT694_13240

BMOB:

MLA2C4_13375

BALU:

QRY64_18565

BPU:

BPUM_0282

BPUM:

BW16_01765

BPUS:

UP12_01740

BALT:

CFN77_01765

BAER:

BAE_09305

BSAF:

BSL056_01705

BCAB:

EFK13_05945(ntdC)

BACW:

QR42_01720

BACY:

QF06_04200

BACL:

BS34A_11670(ntdC)

BALM:

BsLM_1096

BZH:	NF868_01580

BAEI:

RE735_17405

BGI:	BGM20_20540

SFF:	FOB90_09085

PCHI:

PC41400_15400

MAB:

MAB_2612

MMV:	MYCMA_1412

MABB:

MASS_2570

MABL:

MMASJCM_2589

MIZ:	BAB75_14145

MSAO:

MYCSP_09810

SMA:	SAVERM_832

SHAW:

CEB94_31520

SVD:	CP969_03720

SKG:	KJK29_07485

MSIL:

METEAL_26030(ntdC)

» show all

Reference

1 [PMID:23586652]

Authors

Vetter ND, Langill DM, Anjum S, Boisvert-Martel J, Jagdhane RC, Omene E, Zheng H, van Straaten KE, Asiamah I, Krol ES, Sanders DA, Palmer DR

Title

A previously unrecognized kanosamine biosynthesis pathway in Bacillus subtilis.

Journal

J Am Chem Soc 135:5970-3 (2013)
DOI:10.1021/ja4010255

Sequence

[bsu:BSU10530]

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.361

IUBMB Enzyme Nomenclature:

1.1.1.361

ExPASy - ENZYME nomenclature database:

1.1.1.361

BRENDA, the Enzyme Database:

1.1.1.361

DBGET integrated database retrieval system