Entry
Name
scyllo-inositol 2-dehydrogenase (NAD+);
iolX (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
scyllo-inositol:NAD+ 2-oxidoreductase
Reaction(IUBMB)
scyllo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH + H+ [RN:
R09953 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, found in the bacterium Bacillus subtilis, has no activity with NADP+ [cf. EC
1.1.1.371 , scyllo-inositol 2-dehydrogenase (NADP+)]. It is part of a scyllo-inositol degradation pathway leading to acetyl-CoA.
History
EC 1.1.1.370 created 2014
Pathway
ec00562 Inositol phosphate metabolism
ec01120 Microbial metabolism in diverse environments
Orthology
K16043 scyllo-inositol 2-dehydrogenase (NAD+)
Genes
BAZ : BAMTA208_05090(yisS)
BSON : S101395_03659(iolX)
PARG : PspKH34_20940(iolX)
» show all
Taxonomy
Reference
Authors
Morinaga T, Ashida H, Yoshida K
Title
Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 1.1.1.370