KEGG ENZYME: 1.1.1.371

ENZYME: 1.1.1.371

Entry

EC 1.1.1.371                Enzyme

Name

scyllo-inositol 2-dehydrogenase (NADP+);
iolW (gene name)

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

scyllo-inositol:NADP+ 2-oxidoreductase

Reaction(IUBMB)

scyllo-inositol + NADP+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+ [RN:R09954]

Reaction(KEGG)

R09954

Substrate

scyllo-inositol [CPD:C06153];
NADP+ [CPD:C00006]

Product

2,4,6/3,5-pentahydroxycyclohexanone [CPD:C00691];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

The enzyme, found in the bacterium Bacillus subtilis, has no activity with NAD+ [cf. EC 1.1.1.370, scyllo-inositol 2-dehydrogenase (NAD+)].

History

EC 1.1.1.371 created 2014

Pathway

ec00562

Inositol phosphate metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K16044

scyllo-inositol 2-dehydrogenase (NADP+)

Genes

BSU:	BSU33530(yvaA)

BSR:

I33_3473

BSL:

A7A1_2571

BSH:	BSU6051_33530(yvaA)

BSY:	I653_16240

BSUT:

BSUB_03581(iolW)

BSUL:

BSUA_03581(iolW)

BSUS:

Q433_18400

BSO:	BSNT_09872(yvaA)

BSN:	BSn5_07685

BSQ:	B657_33530(yvaA)

BSX:	C663_3223(yvaA)

BSP:	U712_16785

BSS:	BSUW23_16430(yvaA)

BST:

GYO_3666

BIT:	BIS30_06390

BLI:	BL00819(yvaA)

BLD:	BLi03572(yvaA)

BLH:	BaLi_c36330(yvaA)

BAY:	RBAM_030710

BAQ:	BACAU_3096(yvaA)

BYA:	BANAU_3261(yvaA)

BAMP:

B938_15725

BQY:	MUS_3672(yvaA)

BAML:

BAM5036_2984(yvaA)

BAMA:

RBAU_3203(yvaA)

BAMN:

BASU_2989(yvaA)

BAMB:

BAPNAU_3268(yvaA)

BAMT:

AJ82_17360

BAMY:

V529_33330(yvaA)

BMP:	NG74_03240(yvaA)

BAO:	BAMF_3201(yvaA)

BAZ:	BAMTA208_17000(yvaA)

BQL:

LL3_03484

BXH:	BAXH7_03471(yvaA)

BAMI:

KSO_003795

BAMC:

U471_31860

BAMF:

U722_16505

BSIA:

CWD84_03735

BAE:	BATR1942_14725

BVM:	B9C48_15700

BSON:

S101395_04298

BHT:	DIC78_14365

BMOJ:

HC660_32380(iolW)

BTEQ:

G4P54_17195

BIQ:	AN935_16880

BGY:	BGLY_3959(yvaA)

BCAB:

EFK13_17210

BRY:	M0696_16905

BJS:

MY9_3401

BACP:

SB24_13380

BACB:

OY17_18680

BACY:

QF06_15110

BACL:

BS34A_36590(yvaA)

BALM:

BsLM_3363

BACS:

AUL54_14255

BMQ:

BMQ_2694

BMD:

BMD_2681

BMH:	BMWSH_2518(yvaA)

BMEG:

BG04_5160

PKS:	IE339_07360

BGI:	BGM20_10900

BSJ:	UP17_10730

BMUR:

ABE28_010850

PBUT:

DTO10_24350

PFRI:

L8956_11675

MDG:	K8L98_11945

SEDD:

ERJ70_18110

GAJ:	MY490_10880

ECTO:

MUG87_10660

ACIT:

HPK19_05365

» show all

Reference

1 [PMID:20133360]

Authors

Morinaga T, Ashida H, Yoshida K

Title

Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis.

Journal

Microbiology 156:1538-46 (2010)
DOI:10.1099/mic.0.037499-0

Sequence

[bsu:BSU33530]

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.371

IUBMB Enzyme Nomenclature:

1.1.1.371

ExPASy - ENZYME nomenclature database:

1.1.1.371

BRENDA, the Enzyme Database:

1.1.1.371

DBGET integrated database retrieval system