Entry |
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Name |
dimethylmalate dehydrogenase;
beta,beta-dimethylmalate dehydrogenase
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Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
|
Sysname |
(R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)
|
Reaction(IUBMB) |
(R)-3,3-dimethylmalate + NAD+ = 3-methyl-2-oxobutanoate + CO2 + NADH [RN: R01211]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Requires K+ or NH4+ and Mn2+ or Co2+; also acts on (R)-malate.
|
History |
EC 1.1.1.84 created 1972
|
Pathway |
ec00770 | Pantothenate and CoA biosynthesis |
|
Reference |
|
Authors |
Magee PT, Snell EE. |
Title |
The bacterial degradation of pantothenic acid. IV. Enzymatic conversion of aldopantoate to alpha-ketoisovalerate. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 1.1.1.84 |
ExPASy - ENZYME nomenclature database: | 1.1.1.84 |
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